王守宇



姓    名:王守宇

职    称:青年副研究员

电子邮箱:shouyu_wang@fudan.edu.cn

办公地点:上海市徐汇区东安路131号复旦大学枫林校区东12号楼302




教育经历:

2009.09—2014.06 皖南医学院法医学院 法医学专业 本科生

2014.09—2017.06 苏州大学基础医学与生物科学学院 法医学专业 硕士研究生

2017.09—2020.12 四川大学华西基础医学与法医学院 法医学专业 博士研究生

2019.10—2020.11 瑞士苏黎世大学法医学研究所 国家留学基金委公派联合培养


工作经历:

2021.01—2023.05 复旦大学基础医学院 博士后

2023.06—至今 复旦大学基础医学院法医学系 青年副研究员


研究方向:

1. 不明原因猝死的遗传背景及病理机制研究

2. RNA生物物证在法庭科学领域的应用研究


科研项目:

2021,国家自然科学基金青年项目,“辅酶Q10缺陷相关遗传变异参与不明原因猝死的病理机制探索研究”,主持

2021,中国博士后科学基金面上项目,“辅酶Q缺陷通过影响恶性心律失常易感性参与心源性猝死的分子机制探索研究”,主持


课程讲授:

本科生课程:

简明法医学、MBBS Forensic Medicine

研究生课程:

FIST现代法医学研究进展


代表性论著(不超过10/部):

  1. Wang S.#, Chen Y.#, Du J.#, Wang Z., Lin Z., Hong G., Qu D., Shen Y., Li L.*, Post mortem genetic analysis of sudden unexplained death in a young cohort: a whole exome sequencing study, Int J Legal Med. Published online 25 August, 2023.

  2. Wang S.#, He M.#, Andersen J., Lin Y., Zhang M., Tang X., Liu Z., Li L.*, Sudden unexplained death in schizophrenia patients: an autopsy based comparative study from China, Asian J Psychiatr. 79: 103314, 2023.

  3. Hanson E., Dørum G., Zamborlin M., Wang S., Gysi M., Ingold S., Lagace R., Roth C., Haas C., Ballantyne J.*, Targeted S5 RNA sequencing assay for the identification and direct association of common body fluids with DNA donors in mixtures, Int J Legal Med. 137: 13-32, 2023.

  4. Zhang M.#, Wang S.#, Tang X., Ye X., Chen Y., Liu Z., Li L.*, Use of potassium ion channel and spliceosome proteins as diagnostic biomarkers for sudden unexplained death in schizophrenia, Forensic Sci Int. 340: 111471, 2022.

  5. Xu C.#, Yu B.#, Zhao X.#, Lin X., Tang X., Liu Z., Gao P., Ge J., Wang S.*, Li L.*, Valosin Containing Protein as a Specific Biomarker for Predicting the Development of Acute Coronary Syndrome and Its Complication, Front Cardiovasc Med. 9: 803532, 2022.

  6. Wang S., Shanthan G., Bouzga M.M., Dinh H.M.T., Haas C.*, Fonneløp A.E.*, Evaluating the performance of five up-to-date DNA/RNA co-extraction methods for forensic application, Forensic Sci Int. 328: 110996, 2021.

  7. Neubauer J.#*, Wang S.#, Russo G., Haas C., Re-evaluation of single nucleotide variants and identification of structural variants in a cohort of 45 sudden unexplained death cases, Int J Legal Med. 135: 1341-1349, 2021.

  8. Wang S.#, Tao R.#, Ming T., Wang M., Liu J., He G., Zou X., Wang Z.*, Hou Y.*, Expression profile analysis and stability evaluation of 18 small RNAs in the Chinese Han population, Electrophoresis. 41: 2021-2028, 2020.

  9. Wang S.#, Wang Z.#, Tao R., Wang M., Liu J., He G., Yang Y., Xie M., Zou X., Hou Y.*, Expression profile analysis of piwi-interacting RNA in forensically relevant biological fluids, Forensic Sci Int Genet. 42: 171-180, 2019.

  10. Wang S.#, Wang Z.#, Tao R., He G., Liu J., Li C., Hou Y.*, The potential use of Piwi-interacting RNA biomarkers in forensic body fluid identification: A proof-of-principle study, Forensic Sci Int Genet. 39: 129-135, 2019.


#denotes co-first authors, *denotes corresponding authors.