Introduction to Immunology
Teaching contents：
Immunity，Immunology and the functions of immune system Features of innate and adaptive immunity and their relationship The components of immune system The evolution of immunology
Antibodies and Antigen
Teaching contents：
1．Features of antigens: hapten，immunogen and antigenic determinant or epitope
2．Structure of an antibody molecule
3．Structure features of antibodies and their relationship to functions；
4. Human antibody isotypes and functions
MHC
Teaching contents：
Properties of MHC genes：polymorphic and polygenic Structures and expression of class I and class II MHC molecules Characteristics of peptide-MHC Interactions
Antigen Processing and Presentation to T Lymphocytes
Teaching contents：
1．Types of Antigen-Presenting Cells for CD4+ T cells
2．Properties of antigens recognized by T lymphocytes
3．Comparative features of class II and class I MHC pathways of antigen
processing and presentation
Innate Immunity
Teaching contents：
Features of innate immunity Components of the innate immune system Effector mechanisms of innate immunity
4．Role of innate immunity in stimulating adaptive immune responses
T cell and T cell-Mediated Immunity
Teaching contents：
1．Structure of the ab TCR and its role in the recognition of MHC-associated peptide antigen
2．Accessory molecules of T cells
3．Subsets of T cells and their biological properties
4．T cell development
5．Antigen recognition，activation，proliferation and differentiation of T cells
6．Effector mechanisms of T cell-mediated immunity
B cell and B cell-Mediated Immunity
Teaching contents：
Structure of the BCR complex and its role in the recognition of antigens Accessory molecules of B cells Subsets of B cells and their biological properties B cell development Antigen recognition，activation，proliferation and differentiation of B cells Effector mechanisms of humornal immunity
Immunologic tolerance
Teaching contents：
General features and mechanisms of immunologic tolerance Central tolerance Peripheral tolerance
Hypersensitivity
Teaching contents：
Types of hypersensitivity diseases Effector mechanisms of immunologic diseases: diseases caused by antibodies，diseases caused by T lymphocytes Therapeutic approaches for immunologic diseases
Autoimmunity
Teaching contents：
Pathogenesis of autoimmunity and typical diseases Related factors involved in autoimmune diseases Therapeutic approaches for autoimmune diseases
Immunity to tumors
Teaching contents：
General features of tumor immunity Tumor antigens Immune responses to tumors Evasion of immune responses by tumors
Transplantation Immunology
Teaching contents：
1．The immunology of allogenic transplantation: direct and indirect recognition
2．Effector mechanisms of allograft rejection: hyperacute rejection，acute rejection，chronic rejection
3．Prevention and treatment of allograft rejection
