代表性论文 | 近5年的论文：
1. Min, Q., Li, Y., Wu, X., Yu, M., Ying, W., Zhou, Q., Hou, J., Sun, B., Hui, X., Dong, L., Meng, X., Zhang, H., Hu, Z., Feng, X., Sun, J., Wang, W., Wang, X. and Wang, J.-Y. Intrinsic functional defects in B cells of patients with NFKB2 mutations. Clin. Exp. Immunol., in press (2024). 共通讯 2. Zhou, J., Qian, M., Jiang, N., Wu, J., Feng, X., Yu, M., Min, Q., Xu, H., Yang, Y., Yang, Q., Zhou, F., Shao, L., Zhu, H., Yang, Y., Wang, J.-Y., Ruan, Q. and Zhang W. A novel homozygous RHOH variant associated with T cell dysfunction and recurrent opportunistic infections. J. Cli. Immunol. 44: 131 (2024). 共通讯 3. Meng, X., Zhang, H., Dong, L., Min, Q., Yu, M., Li, Y., Liu, L., Wang, W., Ying, W., Sun, J., Wang, J.-Y., Hou, J. and Wang, X. Impact of different genetic mutations on granulocyte development and G-CSF responsiveness in congenital neutropenia. Blood Adv. 8: 1667-1682 (2024). 共通讯 4. Tang, Y., Feng, X., Lu, Q., Cui, C., Yu, M., Wen, Z., Luan, Y., Dong, L., Hu, Z., Zhang, R., Liu, J., Shinkura, R., Hase, K. and Wang, J.-Y. MZB1-mediated IgA secretion suppresses the development and progression of colorectal cancer triggered by gut inflammation. Mucosal Immunol. 17: 450-460 (2024). 通讯作者 5. Wang, C., Sun, B., Wu, K., Farmer, J.R., Ujhazi, B., Geier, C.B., Gordon, S., Westermann-Clark, E., Savic, S., Secord. E., Ravishankar, S., Chen, K., Jin, J.J., Dutmer, C.M., Kanariou, M.G., Adeli, M., Palma, P., Bonfim, C.M.S., Lykopoulou, E., Wolska-Kusnierz, B., Dbaibo, G., Bleesing, J., Moshous, D., Neven, B., Schuetz, C., Geha, R.S., Notarangelo, L.D., Miano, M., Buchbinder, D.K., Csomos, K., Wang, W., Wang, J.-Y, Wang, X., and Walter, J.E. Clinical, immunological features, treatments and outcomes of autoimmune hemolytic anemia in patients with RAG deficiency. Blood Adv. 8: 603-607 (2024). 6. Min, Q., Walter, E.J., Schroeder, H.W., Burrows, P.D. and Wang, J.-Y. Editorial: Mechanisms of dysregulated antibody responses in inborn errors of immunity. Front. Immunol. 14: 1335217 (2023). 通讯作者 7. Min, Q., Csomos, K., Li, Y., Dong, L., Meng, X., Yu, M., Walter J.E. and Wang, J.-Y. B cell abnormalities and autoantibody production in patients with partial RAG deficiency. Front. Immunol. 14: 1155380 (2023). 通讯作者 8. Hao, Q., Zhan, C., Lian, C., Luo, S., Cao, W., Wang, B., Xie, X., Ye, X., Gui, T., Voena, C., Pighi, C., Wang, Y., Tian, Y., Wang, X., Dai, P., Cai, Y., Liu, X., Ouyang, S., Sun, S., Hu, Q., Liu, J., Ye, Y., Zhao, J., Lu, A., Wang, J.-Y., Huang, C., Su, B., Meng, F.L., Chiarle, R., Pan-Hammarström, Q. and Yeap, L.S. DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification. Sci. Immunol. 8(81): eade1167 (2023). 9. Fornes, O., Jia, A., Kuehn, H.S., Min, Q., Pannicke, U., Schleussner, N., Thouenon, R., Yu, Z., de Los Angeles Astbury, M., Biggs, C.M., Galicchio, M., Garcia-Campos, J.A., Gismondi, S., Gonzalez Villarreal, G., Hildebrand, K.J., Hönig, M., Hou, J., Moshous, D., Pittaluga, S., Qian, X., Rozmus, J., Schulz, A.S., Staines-Boone, A.T., Sun, B., Sun, J., Uwe, S., Venegas-Montoya, E., Wang, W., Wang, X., Ying, W., Zhai, X., Zhou, Q., Akalin, A., André, I., Barth, TFE., Baumann, B., Brüstle, A., Burgio, G., Bustamante, J.C., Casanova, J.L., Casarotto, M.G., Cavazzana, M., Chentout, L., Cockburn, I.A., Costanza, M., Cui, C., Daumke, O., Del Bel, K.L., Eibel, H., Feng, X., Franke, V., Gebhardt, J.C.M., Götz, A., Grunwald, S., Hoareau, B., Hughes, T.R., Jacobsen, E.M., Janz, M., Jolma, A., Lagresle-Peyrou, C., Lai, N., Li, Y., Lin, S., Lu, H.Y., Lugo-Reyes, S.O., Meng, X., Möller, P., Moreno-Corona, N., Niemela, J.E., Novakovsky, G., Perez-Caraballo, J.J., Picard, C., Poggi, L., Puig-Lombardi, M.E., Randall, K.L., Reisser, A., Schmitt, Y., Seneviratne, S., Sharma, M., Stoddard, J., Sundararaj, S., Sutton, H., Tran, L.Q., Wang, Y., Wasserman, W.W., Wen, Z., Winkler, W., Xiong, E., Yang, A.W.H., Yu, M., Zhang, L., Zhang, H., Zhao, Q., Zhen, X., Enders, A., Kracker, S., Martinez-Barricarte, R., Mathas, S., Rosenzweig, S.D., Schwarz, K., Turvey, S.E., Wang, J.-Y. A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency. Sci. Immunol. 8(79): eade7953 (2023). 共通讯 10. Liu, J., Shen, Q., Xie, L., Wang, J.-Y., Li, Y., Chen, J., Fang, X., Tang, X., Qian B. and Xu Hong. Protocol for an open-label, single-arm, multicentre clinical study to evaluate the efficacy and safety of rituximab in the first episode of paediatric idiopathic nephrotic syndrome. BMJ Open 12(10): e064216 (2022). 11. Wang, Y.*, Liu, J.*, Akatsu, C., Zhang, R., Zhang, H., Zhu, H., Liu, K., Zhu, H.Y., Min, Q., Meng, X., Cui, C., Tang, Y., Yu, M., Li, Y., Feng, X., Wei, H., Wen, Z., Ji, S., Weigert, M.G., Tsubata, T. and Wang, J.-Y. LAPTM5 mediates immature B cell apoptosis and B cell tolerance by regulating the WWP2-PTEN-AKT pathway. Proc. Natl. Acad. Sci. USA 119: e2205629119 (2022). 通讯作者 12. Wang, W.*, Min, Q.*, Lai, N.*, Csomos, K., Wang, Y., Liu, L., Meng, X., Sun, J., Hou, J., Ying, W., Zhou, Q., Sun, B., Hui, X., Ujhazi, B., Gordon, S., Buchbinder, D., Schuetz, C., Butte, M., Walter, J.E., Wang, X. and Wang, J.-Y. Cellular mechanisms underlying B cell abnormalities in patients with gain-of-function mutations in the PIK3CD gene. Front. Immunol. 13: 890073 (2022). 共通讯 13. Li, Y.*, Tang, Y.*, Liu, J.*, Meng, X., Wang, Y., Min, Q., Hong, R., Tsubata, T., Hase, K. and Wang, J.-Y. Glia maturation factor-γ is involved in S1P-induced marginal zone B cell chemotaxis and optimal IgM production to T-independent type II antigen. Int. Immunol 34: 35-43 (2022). 通讯作者 14. Min, Q.*, Meng, X.*, Zhou, Q.*, Wang, Y., Li, Y., Lai, N., Xiong, E., Wang, W., Yasuda, S., Yu, M., Zhang, H., Sun, J., Wang, X., Wang, J.-Y. RAG1 splicing mutation causes enhanced B-cell differentiation and autoantibody production. JCI Insight, 6: e148887 (2021). 共通讯 15. Yang, Y., Li, X., Ma, Z., Wang, C., Yang, Q., Byrne-Steele, M., Hong, R., Min, Q., Zhou, G., Cheng, Y., Qin, G., Youngyunpipatkul, J.V., Wing, J.B., Sakaguchi, S., Toonstra, C., Wang, L.-X., Vilches-Moure, J.G., Wang, D., Snyder, M.P., Wang, J.-Y., Han, J. and Herzenberg, L.A. CTLA-4 expression by B-1a cells is essential for immune tolerance. Nat. Commun. 12: 525 (2021). 16. Wei H*. and Wang, J.-Y. Role of polymeric immunoglobulin receptor in IgA and IgM transcytosis. Int. J. Mol. Sci. 22: 2284 (2021). 通讯作者 17. Husain, A., Xu, J., Fujii, H., Nakata, M., Kobayashi, M., Wang, J.-Y., Rehwinkel, J., Honjo, T. and Begum, N.A. SAMHD1-mediated dNTP degradation is required for efficient DNA repair during antibody class switch recombination. EMBO J. 39: e102931 (2020). 18. Lai, N, Liu, L., Lin, L., Cui, C., Wang, Y., Min, Q., Xiong, E., Wang, W., Ying, W., Zhou, Q., Hou, J., Sun, J., Wang, J.-Y., and Wang, X. Effective and safe treatment of a novel IL2RA deficiency with rapamycin. J. Allergy Clin. Immunol. Pract. 8(3): 1132-1135e4 (2020) 19. Hong, R., Lai, N., Xiong, E., Ouchida, R., Sun, J., Zhou, Y., Tang, Y., Hikida, M., Tsubata, T., Tagawa, M., Wang, Y. and Wang, J.-Y. Distinct roles of BCNP1 in B cell development and activation. Int. Immunol. 32: 17-26 (2020). 通讯作者 20. Xiong, E., Li, Y., Min, Q., Cui, C., Liu, J., Hong, R., Lai, N., Wang, Y., Sun, J., Matsumoto, R., Takahashi, D., Hase, K., Shinkura, R., Tsubata, T. and Wang, J.-Y. MZB1 promotes the secretion of J chain-containing dimeric IgA and is critical for the suppression of gut inflammation. Proc. Natl. Acad. Sci. USA 116: 13480-13489 (2019). (Cover story) 通讯作者 21. Hong, R., Lai, N., Ouchida, R., Xiong, E., Zhou, Y., Hikida, M., Tsubata, T., Wang Y.Q. and Wang, J.-Y. The B cell novel protein 1 (BCNP1) regulates BCR signaling and B cell apoptosis. Eur. J. Immunol. 49: 911-917 (2019). (Cover story) 通讯作者 22. Feng, Y.-Y., Tang, M., Suzuki, M., Gunasekara, C., Anbe, Y., Hiraoka, Y., Liu, Y., Grasberger, H., Ohkita, M., Matsumura, Y., Wang, J.-Y. and Tsubata, T. Essential role of NADPH oxidase-dependent production of reactive oxygen species in maintenance of sustained B cell receptor signaling and B cell proliferation. J. Immunol. 202: 2546-2557 (2019). 23. Lai, N., Min, Q., Xiong, E., Liu, J., Zhang, L., Yasuda, S. and Wang, J.-Y. A tetrameric form of CD40 ligand with potent biological activities in both mouse and human primary B cells. Mol. Immunol. 105: 173-180 (2019). 通讯作者
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