代表性论文 | Wang Y#, Qian G#, Zhu L#, Zhao Z#, Liu Y, Han W, Zhang X, Zhang Y, Xiong T, Zeng H, Yu X, Yu X, Zhang X, Xu J*, Zou Q*, Yan D*. HIV-1 Vif suppresses antiviral immunity by targeting STING. Cell Mol Immunol. 19(1), 108-121 (2022). He H#, Liu J#, Li L, Qian G, Hao D, Li M, Zhang Y, Hong X, Xu J, Yan D*.Helicobacter Pylori CagA interacts with SHP-1 to suppress the immune response by targeting TRAF6 for K63-linked ubiquitination. J Immunol. 206(6), 1161-1170 (2021). Zhang Y#, Li M#, Li L, Qian G, Wang Y, Chen Z, Liu J, Fang C, Huang F, Guo D, Chu Y, Yan D*. β-arrestin 2 as an activator of cGAS-STING signaling and target of viral immune evasion. Nat. Commun. 11(1), 6000 (2020). Hao D#, Wang Y#, Li L, Qian G, Liu J, Li M, Zhang Y, Zhou R, Yan D*. SHP-1 suppresses the antiviral innate immune response by targeting TRAF3. FASEB J. 34(9), 12392-12405 (2020). Chen Z#, Zhou R#, Zhang Y#, Hao D, Wang Y, Huang S, Liu N, Xia C, Yissachar N, Chu Y, Yan D*. β-Arrestin 2 quenches TLR signaling to facilitate the immune evasion of EPEC. Gut Microbes 11(5), 1423-1437 (2020). Zhou R#, Chen Z#, Hao D, Wang Y, Zhang Y, Yi X, Lyu LD, Liu H, Zou Q, Chu Y, Ge B, Yan D*. Enterohemorrhagic Escherichia coli Tir inhibits TAK1 activation and mediates immune evasion. Emerg Microbes Infect. 8(1), 734-748(2019). Wang L#, Zhou Y#, Chen Z#, Sun L, Wu J, Li H, Liu F, Wang F, Yang C, Yang J, Leng Q, Zhang Q, Xu A, Shen L, Sun J, Wu D, Fang C, Lu H*, Yan D*, Ge B*. PLCβ2 Negatively Regulates the Inflammatory Response to Virus Infection by Inhibiting Phosphoinositide-mediated Activation of TAK1. Nat. Commun. 10(1), 746-758 (2019). Liu H, Zhang H, Wu X, Ma D, Wu J, Wang L, Jiang Y, Fei Y, Zhu C, Tan R, Jungblut P, Pei G, Dorhoi A, Yan Q, Zhang F, Zheng R, Liu S, Liang H, Liu Z, Yang H, Chen J, Wang P, Tang T, Peng W, Hu Z, Xu Z, Huang X, Wang J, Li H, Zhou Y, Liu F, Yan D, Kaufmann SHE, Chen C, Mao Z, Ge B. Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.Nature. 563(7729), 131-136 (2018). Zheng R, Liu H, Zhou Y, Yan D, Chen J, Ma D, Feng Y, Qin L, Liu F, Huang X, Wang J, Ge B. Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation. J Infect Dis. 218(2), 312-323 (2018). Li C, Wang Y, Li Y, Yu Q, Jin X, Wang X, Jia A, Hu Y, Han L, Wang J, Yang H, Yan D*, Bi Y*, Liu G*. HIF1α-dependent glycolysis promotes macrophage functional activities in protecting against bacterial and fungal infection, Scientific Reports, 8(1), 3603 (2018). Zhuang X#, Chen Z#, He C, Wang L, Zhou R, Yan D*, Ge B*. Modulation of host signaling in inflammatory response by enteropathogenic Escherichia coli virulence proteins. Cell Mol Immunol. 14(3), 237-244 (2017). Si Y, Zhang Y, Chen Z, Zhou R, Zhang Y, Hao D, Yan D*. Posttranslational Modification Control of Inflammatory Signaling., Adv Exp Med Biol, 2017, 1024, 37-61 (2017). Zou B, Jiang W, Han H, Li J, Mao W, Tang Z, Yang Q, Qian G, Qian J, Zeng W, Gu J, Chu T, Zhu N, Zhang W, Yan D, He R, Chu Y, Lu M. Acyloxyacyl hydrolase promotes the resolution of lipopolysaccharide-induced acute lung injury.PLoS Pathog. 13(6):e1006436 (2017). Zhou Y, He C, Yan D, Liu F, Liu H, Chen J, Cao T, Zuo M, Wang P, Ge Y, Lu H, Tong Q, Qin C, Deng Y, Ge B. The kinase CK1ɛ controls the antiviral immune response by phosphorylating the signaling adaptor TRAF3.Nat Immunol. 17(4), 397-405 (2016). Yan D, Farache J, Mingueneau M, Mathis D*, Benoist C*. Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3.Proc Natl Acad Sci U S A 112(48), 14942-14947 (2015). Yan D#, Quan H#, Wang L, Liu F, Liu H, Chen J, Cao X, Ge B*. Enteropathogenic Escherichia coli Tir recruits cellular SHP-2 through ITIM motifs to suppress host immune response. Cell Signal. 25(9), 887-894 (2013). Yan D, Wang X, Luo L, Cao X, Ge B*. Inhibition of TLR signaling by a bacterial protein containing immunoreceptor tyrosine-based inhibitory motifs. Nat Immunol. 13, 1063–1071 (2012). Liu HP, Yu MC, Jiang MH, Chen JX, Yan DP, Liu F, Ge BX. Association of supervillin with KIR2DL1 regulates the inhibitory signaling of natural killer cells.Cell Signal. 23(2), 487-96 (2011). Huang Z, Yan DP, Ge BX. JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin.Cell Signal. 20(11), 2002-12 (2008).
|
