王彦青

发表时间：2023-09-28 阅读次数：4603次

博士、教授、博士生导师

国家中医药管理局针灸神经生物学三级实验室主任（2008- ）

中西医结合学系主任（2013-）

研究方向：慢性痛及针刺、中药镇痛的神经生物学机制研究

建立骨转移型癌痛大鼠模型，从中枢胶质细胞功能活动变化正性和负性调控因素的角度，研究慢性痛和针刺镇痛机理。在J Neuroinflammation、J Pain、Neuropharmacol、Int J Cancer等杂志发表SCI论文多篇，申请发明专利五项，获批一项；近年来承担科技部973子项目、教育部霍英东教育基金会青年教师基金、教育部新世纪优秀人才支持计划、国家自然科学面上项目、资助项目、上海市科委项目等多项课题；2003年被评为“复旦大学世纪之星”，2006年获得“复旦大学优秀世纪之星”称号。

学习和工作简历
1992年毕业于上海医科大学药理学专业；1995年获上海医科大学硕士学位、2000年获博士学位；1992年起先后在复旦大学医学神经生物学国家重点实验室和中西医结合系工作； 2000-2002在日本千叶癌症中心从事博士后研究，任日本科学技术振兴会特别研究员（STA Fellow）。2002年回国继续在上医任职。2006年破格任博士生导师，2009年升为教授。

论文论著
1. Li Q, Yue N, Liu SB, Wang ZF, Mi WL, Jiang JW, Wu GC, Yu J, Wang YQ. Effects of Chronic Electroacupuncture on Depression- and Anxiety-Like Behaviors in Rats with Chronic Neuropathic Pain. Evidence-Based Complementary and Alternative Medicine. 2014; 2014:158987.

2. Wang ZF, Li Q, Liu SB, Mi WL, Hu S, Zhao J, Tian Y, Mao-Ying QL, Jiang JW, Ma HJ, Wang YQ, Wu GC. Aspirin-triggered Lipoxin A4 attenuates mechanical allodynia in association with inhibiting spinal JAK2/STAT3 signaling in neuropathic pain in rats. Neuroscience. 2014 Jul 25;273:65-78.

3. Zhao J, Zhang H, Liu SB, Han P, Hu S, Li Q, Wang ZF, Mao-Ying QL, Chen HM, Jiang JW, Wu GC, Mi WL, Wang YQ. Spinal interleukin-33 and its receptor ST2 contribute to bone cancer-induced pain in mice. Neuroscience 2013 Dec,3, 253:172-182.

4. Li Q, Tian Y, Wang ZF, Liu SB, Mi WL, Ma HJ, Wu GC, Wang J, Yu J, Wang YQ. Involvement of the spinal NALP1 inflammasome in neuropathic pain and aspirin-triggered-15-epi-lipoxin A4 induced analgesia. Neuroscience. 2013 Dec 19;254:230-40.

5. Hu S, Mao-Ying QL, Wang J, Wang ZF, Mi WL, Wang XW, Jiang JW, Huang YL, Wu GC, Wang YQ. Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines. J Neuroinflammation. 2012; 9:278. 4.7

6. Wang XW, Li TT, Zhao J, Mao-Ying QL, Zhang H, Hu S, Li Q, Mi WL, Wu GC, Zhang YQ, Wang YQ. Extracellular signal-regulated kinase activation in spinal astrocytes and microglia contributes to cancer-induced bone pain in rats. Neuroscience. 2012; 217:172-81.

7. Wang XW, Hu S, Mao-Ying QL, Li Q, Yang CJ, Zhang H, Mi WL, Wu GC, Wang YQ. Activation of c-jun N-terminal kinase in spinal cord contributes to breast cancer induced bone pain in rats. Mol Brain. 2012 Jun 9;5:21.

8. Mao-Ying QL, Wang XW, Yang CJ, Li X, Mi WL, Wu GC, Wang YQ. Robust spinal neuroinflammation mediates mechanical allodynia in Walker 256 induced bone cancer rats. Mol Brain. 2012 May 20;5:16.

9. Wang XW, Li TT, Zhao J, Mao-Ying QL, Zhang H, Hu S, Li Q, Mi WL, Wu GC, Zhang YQ, Wang YQ. Extracellular signal-regulated kinase activation in spinal astrocytes and microglia contributes to cancer-induced bone pain in rats. Neuroscience. 2012; 217:172-81.

10. Mi WL, Mao-Ying QL, Wang XW, Li X, Yang CJ, Jiang JW, Yu J, Wang J, Liu Q, Wang YQ, Wu GC. Involvement of spinal neurotrophin-3 in electroacupuncture analgesia and inhibition of spinal glial activation in rat model of monoarthritis. J Pain. 2011; 12:974-84.

11. Tong Z, Luo W, Wang Y, Yang F, Han Y, Li H, Luo H, Duan B, Xu T, Maoying Q, Tan H, Wang J, Zhao H, Liu F, Wan Y. Tumor tissue-derived formaldehyde and acidic microenvironment synergistically induce bone cancer pain. PLoS One. 2010; 5:e10234.

12. Mi WL, Mao-Ying QL, Liu Q, Wang XW, Li X, Wang YQ, Wu GC. The distribution of kisspeptin and its receptor GPR54 in rat dorsal root ganglion and up-regulation of its expression after CFA injection. Brain Res Bull. 2009; 78: 254-60.

13. Mao-Ying QL, Zhao J, Dong ZQ, Wang J, Yu J, Yan MF, Zhang YQ, Wu GC, Wang YQ. A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells. Biochem Biophys Res Commun. 2006; 345:1292-1298.

14. Mao-Ying QL, Cui KM, Liu Q, Dong ZQ, Wang W, Wang J, Sha H,Wu GC, Wang YQ, Stage-dependent analgesia of electro-acupuncture in a mouse model of cutaneous cancer pain. Eur J Pain. 2006; 10:689-694.

15. Dong ZQ, Wang YQ, Ma F, Xie H, Wu GC. Down-regulation of GFRalpha-1 expression by antisense oligodeoxynucleotide aggravates thermal hyperalgesia in a rat model of neuropathic pain. Neuropharmacology. 2006; 50:393-403.

联系方式
Email: wangyanqing@shmu.edu.cn
电话: 021-54237496
传真: 021-54237526
通讯地址: 上海市医学院路138号复旦大学基础医学院中西医结合系291信箱
邮编: 200032