田占庄
博士、副教授、硕士生导师
中西医结合学系副主任(2013-)
研究方向:中西医结合调整神经内分泌紊乱的神经生物学机制
1. 女童性早熟的发病机制及中西医结合治疗性早熟的神经生物学机制
2. 针刺调节下丘脑-垂体-肾上腺轴功能紊乱的神经生物学机制
学习和工作经历
河北医科大学临床医学本科(1985-1990),北京中医药大学中西医结合基础硕士(1993-1996),复旦大学中西医结合基础博士(2000-2003)。
河北省承德医学院解剖教研室助教(1990-1997)、讲师(1997-2003),复旦大讲师(2003-2007)、副教授(2007-至今);2005-2006年作为访问学者在美国密苏里堪撒斯城大学药学院药理系进修。中国神经科学学会会员、中国中西医结合学会儿科专业委员会委员、中国针灸学会针刺麻醉分会副秘书长。主持或参与多项国家重点基础研究计划(973)和国家自然科学基金课题。目前在研国家自然科学基金一项(No. 81273894,NKB/dynorphin参与kisspeptin /GPR54介导的滋阴泻火中药合剂治疗性早熟的神经机制, 70万元,2013.1—2016.12);国家重点基础研究计划(973)课题一项(2013CB531906针药复合麻醉机体保护机制研究)。2005年作为主要完成人获上海市科技进步二等奖一项,中国中西医结合学会科学技术奖三等奖一项。
论文论著
1.Shiran Wang, Liting Zhu, Jian Yu, Zhanzhuang Tian. Effect of Nourishing“Yin”-removing “Fire” Chinese herbal mixture on hypothalamic NKB/NK3R expression in female precocious rats. Evidence-Based Complementary and Alternative Medicine 2014, Article ID 217424, http://dx.doi.org/10.1155/2014/217424
2. Jing Li, Yanyan Sun, Shiran Wang, Jian Yu, Zhanzhuang Tian. Effects of Nourishing “Yin”-Removing “Fire” Chinese Herb Mixture on the Differential Expression of GABAA Receptor α Subunits in Hypothalamus of Precocious Puberty Female Rats. Chinese Medicine, 2013, 4, 87-96
3. Yan Sun, Jian Yu, Boying Chen , Zhanzhuang Tian. Effect of Nourishing ″Yin″- Removing ″Fire″ Chinese herb mixture on the hypothalamic kisspeptin expression in precocious rats. Journal of Ethnopharmacology, 2010,127:274-279
4. Li Sun, Zhanzhuang Tian , Jianping Wang. A direct cross-talk between interferon-c and sonic hedgehog signaling that leads to the proliferation of neuronal precursor cells. Brain, Behavior, and Immunity 24 (2010) 220–228
5. Hua Zhang, Zhanzhuang Tian, Jianping Wang. Behavioral evaluation of transgenic mice with CNS expression of IFN-a by elevated plus-maze and Porsolt swim test . Neurosci Lett. 2010,479: 287-291.
6. Yan Sun, Zhan-Zhuang Tian, Hong Zhao, Stephen TC Wong, Bo-Ying Chen. Characteristic of hypothalamic kisspeptin expression in the pubertal development of precocious female rats. Neurosci Lett. 2007,420:12-17.
7. Zhan-Zhuang Tian, Hong Zhao, Bo-Ying Chen. Evaluation of the true precocious puberty rats induced by neonatal administration of Danazol: Therapeutic effects of nourishing “Yin”- removing “Fire” Chinese herb mixture. Reprod Biol & Endocrin 2005,3:38.
8. Zhan-Zhuang Tian, Hong Zhao, Bo-Ying Chen. Decreased hypothalamic aromatase in female rats of precocious puberty. Neurosci Lett, 2004, 366(1): 92-96.
9. Hong Zhao, Zhan-Zhuang Tian, Jun-Wei Hao, Bo-Ying Chen. Extragonadal aromatization increases with time after ovariectomy in rat. Reprod Biol & Endocrin, 2005, 3:6.
10. Hong Zhao, Zhan-Zhuang Tian, Bo-Ying Chen. Brain aromatization may involve in electroacupuncture enhancing hypofunction of hypothalamus- pituitary - ovary axis in ovariectomized rats. Brain Res, 2005, 1037 (1-2):164-170.
11. Hong Zhao, Zhan-Zhuang Tian, Yi Feng, Bo-Ying Chen. Circulating estradiol and hypothalamic corticotrophin releasing hormone enhances along with time after ovariectomy in rats: effects of electroacupuncture. Neuropeptides 2005, 39(4): 433-438.
12. Hong Zhao, Zhan-Zhuang Tian, Bo-Ying Chen. Increased corticortropin- releasing hormone release in ovariectomized rats’ paraventricular nucleus: effects of electroacupuncture. Neurosci Lett, 2003, 353(1): 37-40.
13. Hong Zhao, Zhan-Zhuang Tian, Bo-Ying Chen. An important role of corticotropin-releasing hormone in electroacupuncture normalizing the subnormal function of hypothalamus- pituitary-ovary axis in ovariectomized rats. Neurosci Lett, 2003, 349(1): 25-28
14. 田占庄,赵 宏,陈伯英. 滋阴泻火中药对性早熟模型大鼠促性腺激素释放激素及其受体mRNA表达的影响 中国中西医结合杂志2003,23(9): 700-704.
15. 田占庄,赵 宏,陈伯英. 达那唑诱导的雌性性早熟大鼠GnRH及其受体mRNA的表达 中华内分泌代谢杂志 2003,19(3): 229-231.
16. 陈姗姗,俞健,田占庄. 曲谱瑞林治疗真性性早熟的中枢机制 中国新药与临床杂志 2009 28(2):134-137。
17. 张彦,马淑兰,陈伯英,田占庄. 针刺对急性手术创伤大鼠下丘脑CRF家族肽及其受体表达的影响,针刺研究,2010, 35(3):163-169.
18. 朱黎婷,田占庄.电针对急性手术创伤大鼠海马及下丘脑促肾上腺皮质激素释放因子表达的影响[J]. 针刺研究, 2013, 38(5):369-374
19. 田占庄,张立凤,朱培纯. 两种慢性痛大鼠脊髓和脊神经节一氧化氮合酶的表达及电针的影响. 承德医学院学报 2001,18(3) 198-201.
20. 田占庄,张立凤,朱培纯.两种慢性痛大鼠脊神经节生长抑素mRNA的表达及电针的影响. 承德医学院学报 2001, 18(4)267-271.
21. Zhan Zhuang Tian, Zhao Hong: Acupuncture Therapy for Menopausal and Perimenopausal Syndrome (Editors: Ying Xia, Xiaoding Cao, Gencheng Wu, Jieshi Cheng, Acupuncture therapy for neurological diseases: A neurobiological view). TSINGHUA and Springer; 1st Edition 2010
联系方式
E-mail: tianvv@shmu.edu.cn
电话:021-54237611, 传真:021-54237526
通讯地址:上海医学院路138号,复旦大学基础医学院中西医结合系291信箱, 200032