姓 名:王露
职 称:副教授
联系电话:13761831993
电子邮箱:luwang1@fudan.edu.cn
办公地点:上海市徐汇区东安路130号西7号楼119室
个人主页/课题组网页:
教育经历:
1999.09—2003.06 华东师范大学生物科学专业本科生
2003.09—2006.06 华东师范大学分子神经生物学专业硕士研究生
2006.09—2010.10 法国巴黎第六大学神经科学专业博士研究生
工作经历:
2011.03—2014.04 中科院神经所 助理研究员
2014.05—2017.12 复旦大学基础医学院药理学系 青年副研究员
2018.01—至今 复旦大学基础医学院药理学系 副教授
研究方向:
1.纹状体环路功能、可塑性,及其在焦虑性失眠等睡眠障碍中的作用和机制
2.全身麻醉药引起意识消失的神经机制
科研项目:
2019,国家自然科学基金面上项目,“伏隔核PV中间神经元调控睡眠觉醒的作用和机制”,主持
2015,国家自然科学基金面上项目,“伏隔核整合睡眠和学习记忆的神经生物学机制”,主持
讲授课程:
本科生课程:
药理学、循环血液疾病基础、功能学实验、医学生综合素养
研究生课程:
高级神经药理学、临床药理学、高级药理学进展
代表性论著:
1. Wang RF#, Guo H#, Jiang SY, Liu ZL, Qu WM, Huang ZL*, Wang L*. Control of wakefulness by lateral hypothalamic glutamatergic neurons in male mice. J Neurosci Res, 2021; 99(6):1689-1703.
2. Xu W#, Wang L#, Yuan XS, Wang TX, Li WX, Qu WM, Hong ZY, Huang ZL*. Sevoflurane depresses neurons in the medial parabrachial nucleus by potentiating postsynaptic GABAA receptors and background potassium channels. Neuropharmacology, 2020; 181:108249.
3. Gong WK, Ni J, Yu LF, Wang L*, Huang ZL*. Temporal dynamics of Arc/Arg3.1 expression in the dorsal striatum during acquisition and consolidation of a motor skill in mice. Neurobiol Learn Mem, 2020; 168:107156.
4. Luo YJ#, Li YD#, Wang L#, Yang SR, Yuan XS, Wang J, Cherasse Y, Lazarus M, Chen JF, Qu WM*, Huang ZL*. Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D1 receptors. Nat Commun, 2018; 9(1):1576.
5. Tan GH#, Liu YY#, Wang L#, Li K#, Zhang ZQ, Li HF, Yang ZF, Li Y, Li D, Wu MY, Yu CL, Long JJ, Chen RC, Li LX, Yin LP, Liu JW, Cheng XW, Shen Q, Shu YS, Sakimura K, Liao LJ, Wu ZY, Xiong ZQ*. PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum. Cell Res, 2018 Jan;28(1):90-110.
6. Oishi Y#, Xu Q#, Wang L#, Zhang BJ, Takahashi K, Takata Y, Luo YJ, Cherasse Y, Schifmann S, de Kerchove d'Exaerde A, Urade Y, Qu WM, Huang ZL* and Lazarus M*. Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice. Nat Commun, 2017; 8(1):734.
7. Yuan XS#, Wang L#, Dong H#, Qu WM, Yang SR, Cherasse Y, Lazarus M, Schifmann S, de Kerchove d'Exaerde A, Li RX* and Huang ZL*. Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus. eLife, 2017; 6:e29055.
8. Sun Y, Jiang SY, Ni J, Luo YJ, Chen CR, Hong ZY, Yanagawa Y, Qu WM, Wang L*, Huang ZL*. Ethanol inhibits histaminergic neurons in mouse tuberomammillary nucleus slices via potentiating GABAergic transmission onto the neurons at both pre- and postsynaptic sites. Acta Pharmacol Sin, 2016; 37(10):1325-1336.
9. Wang L, Tu P, Bonet L, Aubrey K, and Supplisson S*. Cytosolic transmitter concentration regulates vesicle cycling at hippocampal GABAergic terminals. Neuron, 2013; 80(1):143-158.
10. Wang L, Bai J, Hu YH. Identification of the RA response element and transcriptional silencer in human alphaCaMKII promoter. Mol Biol Rep, 2008; 35(1):37-44.