姓名：魏晓丽
职称：青年研究员
电话：021-54237379
电子邮箱：xlwei@fudan.edu.cn
办公地点：上海市徐汇区东安路130号西13号楼
个人主页/课题组网页
教育经历：
2005.09—2009.06四川大学华西药学院本科生
2009.09—2014.06复旦大学药剂学专业博士研究生
工作经历：
2014.09—2016.11复旦大学生物学流动站（医口）博士后
2015.09—2019.11加州大学圣地亚哥分校博士后
2020.09—至今复旦大学基础医学院青年研究员
获得人才项目：
2021，上海市海外高层次人才引进计划，上海市组织部
获得奖项：
2017，教育部自然科学奖二等奖，中国教育部
2016，上海市研究生优秀成果（学位论文）奖，上海市教育委员会
研究方向：
纳米药物制剂/疫苗用于恶性肿瘤及细菌感染等重大疾病防治研究
科研项目：
2016，中国博士后科学基金面上资助一等资助，“稳定性多肽介导脑靶向的红细
胞膜包被纳米递药系统研究”，主持
课程讲授：
本科生课程：药理学
学术兼职：2022-今Nano Lett杂志青年编委
代表性论著：
1.Li, G.#, Wang, M.#, Ding, T., Wang, J., Chen, T., Shao, Q., Jiang, K., Wang, L., Yu, Y., Pan, F., Wang, B.*, Wei, X.*, Qian, J.*, Zhan, C. cRGD enables rapid phagocytosis of liposomal vancomycin for intracellular bacterial clearance. J Control Release, 2022, 344: 202-213
2.Wei, X.#, Ran, D.#, Campeau, A., Xiao, C., Zhou, J., Dehaini, D., Jiang, Y., Kroll, V., Zhang, Q., Gao, W., Gonzalez, D., Fang, R.*, Zhang, L.* Multiantigenic nanotoxoids for antivirulence vaccination against antibiotic-resistant gram-negative bacteria. Nano Lett 2019, 19(7): 4760-9
3.Wei, X.#, Beltrán-Gastélum, M.#, Karshalev, E., Esteban-Fernández de Ávila, B., Zhou, J., Ran, D., Angsantikul, P., Fang, R., Wang, J.*, Zhang, L.* Biomimetic micromotor enables active delivery of antigens for oral vaccination. Nano Lett 2019, 19(3): 1914-21
4.Wei, X.#, Zhang, G.#, Ran, D., Krishnan, N., Fang, R., Gao, W., Spector, S., Zhang, L.* T-cell-mimicking nanoparticles can neutralize HIV Infectivity. Adv Mater 2018, 30(45): 1802233
5.Wei, X., Ying, M., Dehaini, D., Su, Y., Kroll, A., Zhou, J., Gao, W., Fang, R., Chien, S., Zhang, L.* Nanoparticle functionalization with platelet membrane enables multifactored biological targeting and detection of atherosclerosis. ACS Nano 2018, 12(1): 109-116
6.Wei, X.#, Gao, J.#, Wang, F., Ying, M., Angsantikul, P., Kroll, A., Zhou, J., Gao, W., Lu, W., Fang, R., Zhang, L.* In situ capture of bacterial toxins for antivirulence vaccination. Adv Mater 2017, 29(33): 1701644
7.Wei, X.#, Gao, J.#, Fang, R., Luk, B., Kroll, A., Dehaini, D., Zhou, J., Kim, H., Gao, W., Lu, W., Zhang, L.* Nanoparticles camouflaged in platelet membrane coating as an antibody decoy for the treatment of immune thrombocytopenia. Biomaterials 2016, 111:116-123
8.Wei, X., Zhan, C.*, Shen, Q., Fu, W., Xie, C., Gao, J., Peng, C., Zheng, P., Lu, W.* A D-peptide ligand of nicotine acetylcholine receptors for brain-targeted drug delivery. Angew Chem Int Ed Engl 2015, 54(10): 3023-7
9.Wei, X., Gao, J., Zhan, C., Xie, C., Chai, Z., Ran, D., Ying, M., Zheng, P., Lu, W.* Liposome-based glioma targeted drug delivery enabled by stable peptide ligands. J Control Release 2015, 218: 13-21
10.Wei, X., Zhan, C., Chen, X., Hou, J., Xie, C., Lu, W.* Retro-inverso isomer of angiopep-2: a stable D-peptide ligand for inspiring brain-targeted drug delivery. Mol Pharmaceut 2014, 11(10): 3261-8
代表性专利：
1.一种乙酰胆碱受体介导靶向的D构型多肽及其应用 (已授权：ZL201310513197 .4）