蒋维
发表时间：2020-10-21 阅读次数：1436次
蒋维，青年研究员，博士生导师，上海市高校“东方学者”特聘教授。
教育及工作经历：
2002/9-2006/6， 武汉大学生命科学院，理学学士
2007/9-2012/12， 复旦大学生命科学院，遗传学博士
2013/9-2016/9， 复旦大学基础医学院，博士后
2016/10-2018/11，美国加州大学旧金山分校，博士后
2019/1-至今， 复旦大学基础医学院，青年研究员
联系方式：
Email：jiangw@fudan.edu.cn
电话：021-54237927
地址：上海市东安路130号西13号楼507室
主要研究方向：
1、压力应激蛋白在肿瘤恶性进程中的作用机制；
2、氧气应激介导的蛋白质脯氨酸羟基化修饰调控机制。
近期研究成果：
蒋维博士主要从事压力应激蛋白，以及氧气应激所介导的羟基化修饰在肿瘤等重大疾病中的作用机制研究，近年来在ELife、Blood、Oncogene、Hepatology和Nat Biomed Eng等期刊上发表研究论文20余篇，引用近600次。先后获得国家自然科学基金委员会青年基金、面上项目，中国博士后基金会国际派出计划、上海市教育委员会和复旦大学高峰人才引进启动经费等资助。
代表性论文：
[1] R. Tan, W. Du, Y. Liu, X. Cong, M. Bai, C. Jiang, Z. Li, M. Tan, DK. Ma, Q. Huang*, W. Jiang*, Y. Dang*, Nucleolus localization of SpyCas9 affects its stability and interferes with host protein translation in mammalian cells. Genes & Diseases, (2020), accepted.
[2] D. Ding#, H. Huang#, Q. Li#, W. Yu, C. Wang, H. Ma, J. Wu, Y. Dang, L. Yu*, W. Jiang*, NF90 stabilizes cyclin E1 mRNA through phosphorylation of NF90-Ser382 by CDK2, Cell Death Discov, 6 (2020) 3.
[3] W. Jiang#, X. Zhou#, Z. Li#, K. Liu, W. Wang, R. Tan, X. Cong, J. Shan, Y. Zhan, Z. Cui, L. Jiang, Q. Li, S. Shen, M. Bai, Y. Cheng, B. Li, M. Tan, D.K. Ma, J.O. Liu, Y. Dang*, Prolyl 4-hydroxylase 2 promotes B-cell lymphoma progression via hydroxylation of Carabin, Blood, 131 (2018) 1325-1336.
[4] W. Jiang#, Y. Wei#, Y. Long#, A. Owen, B. Wang, X. Wu, S. Luo, Y. Dang, D.K. Ma*, A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans, Elife, 7 (2018).
[5] W. Jiang#, H. Huang, L. Ding, P. Zhu, H. Saiyin, G. Ji, J. Zuo, D. Han, Y. Pan, D. Ding, X. Ma, Y. Zhang, J. Wu, Q. Yi, J.O. Liu, H. Huang, Y. Dang, L*. Yu*, Regulation of cell cycle of hepatocellular carcinoma by NF90 through modulation of cyclin E1 mRNA stability, Oncogene, 34 (2015) 4460-4470.
[6] X. Lin#, Y. Liu#, A. Bai#, H. Cai#, Y. Bai, W. Jiang, H. Yang, X. Wang, L. Yang*, N. Sun*, H. Gao*, A viscoelastic adhesive epicardial patch for treating myocardial infarction, Nat Biomed Eng, 3 (2019) 632-643.
[7] C. Jiang#, Y. Tang#, L. Ding, R#. Tan, X. Li, J. Lu, J. Jiang, Z. Cui, Z. Tang, W. Li, Z. Cao, T. Schneider-Poetsch, W. Jiang, C. Luo, Y. Ding*, J. Liu*, Y. Dang*, Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling, Cell Chem Biol, 26 (2019) 1417-1426 e1415.
[8] Z. Li#, Z. Cheng, C#. Raghothama, Z. Cui, K. Liu, X. Li, C. Jiang, W. Jiang, M. Tan, X. Ni, A. Pandey, J.O. Liu, Y. Dang*, USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1, Nucleic Acids Res, 46 (2018) 823-839.
[9] D. Ding#, H. Huang#, W. Jiang, W. Yu, H. Zhu, J. Liu, H. Saiyin, J. Wu, H. Huang, S. Jiang*, L. Yu*, Reticulocalbin-2 enhances hepatocellular carcinoma proliferation via modulating the EGFR-ERK pathway, Oncogene, 36 (2017) 6747-6748.
[10] Q. Wang#, H. Yang#, A. Bai, W. Jiang, X. Li, X. Wang, Y. Mao, C. Lu, R. Qian, F. Guo, T. Ding, H. Chen, S. Chen, J. Zhang, C. Liu*, N. Sun*, Functional engineered human cardiac patches prepared from nature's platform improve heart function after acute myocardial infarction, Biomaterials, 105 (2016) 52-65.
[11] D.K. Jiang#*, X.P. Ma#, H. Yu#, G. Cao#, D.L. Ding, H. Chen, H.X. Huang, Y.Z. Gao, X.P. Wu, X.D. Long, H. Zhang, Y. Zhang, Y. Gao, T.Y. Chen, W.H. Ren, P. Zhang, Z. Shi, W. Jiang, B. Wan, H. Saiyin, J. Yin, Y.F. Zhou, Y. Zhai, P.X. Lu, H. Zhang, X. Gu, A. Tan, J.B. Wang, X.B. Zuo, L.D. Sun, J.O. Liu, Q. Yi, Z. Mo, G. Zhou, Y. Liu, J. Sun, Y.Y. Shugart, S.L. Zheng, X.J. Zhang, J. Xu*, L. Yu*, Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B, Hepatology, 62 (2015) 118-128.
[12] D.K. Jiang#, J. Sun#, G. Cao#, Y. Liu#, D. Lin#, Y.Z. Gao, W.H. Ren, X.D. Long, H. Zhang, X.P. Ma, Z. Wang, W. Jiang, T.Y. Chen, Y. Gao, L.D. Sun, J.R. Long, H.X. Huang, D. Wang, H. Yu, P. Zhang, L.S. Tang, B. Peng, H. Cai, T.T. Liu, P. Zhou, F. Liu, X. Lin, S. Tao, B. Wan, H.X. Sai-Yin, L.X. Qin, J. Yin, L. Liu, C. Wu, Y. Pei, Y.F. Zhou, Y. Zhai, P.X. Lu, A. Tan, X.B. Zuo, J. Fan, J. Chang, X. Gu, N.J. Wang, Y. Li, Y.K. Liu, K. Zhai, H. Zhang, Z. Hu, J. Liu, Q. Yi, Y. Xiang, R. Shi, Q. Ding, W. Zheng, X.O. Shu, Z. Mo, Y.Y. Shugart, X.J. Zhang, G. Zhou, H. Shen, S.L. Zheng, J. Xu*, L. Yu*, Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma, Nat Genet, 45 (2013) 72-75.