汤妍
汤妍,青年副研究员
教育及工作经历:
2005.09-2010.07 哈尔滨医科大学临床检验本科生
2010.09-2015.07 复旦大学生物化学与分子生物学博士研究生
2015.07-2018.06 复旦大学生物医学研究院博士后
2018.06-至今 复旦大学基础医学院青年副研究员
联系方式:
yantang@fudan.edu.cn
研究领域:
主要从事血管周围脂肪代谢及与心血管疾病研究,发现了心脏周围脂肪棕色化水平与冠心病的相关性,进一步的研究工作发现血管周围脂肪缺失BMP4后可引起血管周围脂肪的炎症状态,从而促发血管内皮的炎症反应,加剧脉粥样硬化的发生。先后获得中国博士后基金面上项目,国家自然科学基金委员会青年项目、面上项目。
在研科研项目:
1. BMP4通过血管周围脂肪调节动脉粥样硬化发生的机制研究编号:81970754,经费:55万元,2020-2023,国家自然科学基金面上项目,项目负责人
近年来科研成果(*共同通讯作者):
1.Wenjuan Mu#, Shuwen Qian#, Yanjue Song, Lijie Yang, Saisai Song, Qiqi Yang, Hao Liu, Yang Liu, Dongning Pan, Yan Tang*, Qi-Qun Tang*, BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis. Redox Biol. 2021 Jul;43:101979.
2.Yan Tang#, Yi He#, Chen Li#, Wenjuan Mu, Ying Zou, Conghui Liu, Shuwen Qian, Fuchuang Zhang, Jiabao Pan, Yina Wang, Haiyan Huang, Dongning Pan, Pengyuan Yang, Ju Mei*, Rong Zeng*, Qi-Qun Tang*, RPS3A positively regulates the mitochondrial function of human periaortic adipose tissue and is associated with coronary artery diseases. Cell Discov. 2018 Aug 21; 4:52.
3.Yan Tang#, Zhang-Yi Pan#, Ying Zou, Yi He, Peng-Yuan Yang, Qi-Qun Tang, Feng Yin*. A comparative assessment of adipose-derived stem cells from subcutaneous and visceral fat as a potential cell source for knee osteoarthritis treatment. J Cell Mol Med. 2017 Sep;21(9):2153-2162.
4.Yan Tang#, Shu-Wen Qian#*, Meng-Yuan Wu, Jue Wang, Ping Lu, Xi Li, Hai-Yan Huang, Liang Guo, Xia Sun, Cong-Jian Xu, Qi-Qun Tang*. BMP4 mediates the interplay between adipogenesis and angiogenesis during expansion of subcutaneous white adipose tissue. J Mol Cell Biol. 2016 Aug;8(4):302-12.
5.Qian Shu-Wen, Tang Yan, Li Xi, Liu Yuan, Zhang You-You, Huang Hai-Yan, Xue Rui-Dan, Yu Hao-Yong, Guo Liang, Gao Hui-Di, Liu Yan, Sun Xia, Li Yi-Ming, Jia Wei-Ping, Tang Qi-Qun *. BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis, Proceedings of the National Academy of Sciences of the United States of America, 2013.2.26, 110(9): E798~E807.
主讲课程:
本科生课程:《生物化学实验》
MBBS:《BiochemistryLab》