徐延勇
徐延勇，2015年毕业武汉大学生物化学与分子生物学专业，获理学博士学位；2016-2018年在美国俄亥俄医科大学进行博士后研究，于2019年晋升为该校研究助理教授。2021年始任复旦大学基础医学院青年研究员并入选上海市领军人才；JBC编委；中国生物化学与分子生物学代谢专业分会委员；中国生物化学与分子生物学脂质与脂蛋白专业委员会委员。迄今以主要作者发表SCI论文20余篇，包括 Dev Cell, Sci Adv, Nat Metab, Hepatology, J Hepatol, Diabetes，Autophagy等，他引累计>1000次。
研究方向
肝脏糖脂代谢紊乱与代谢性疾病调控
脂蛋白代谢与动脉粥样硬化
联系方式021-64033738
地址：东安路130号科研二号楼4楼
邮箱：yanyong_xu@fudan.edu.cn
代表性论文
1. Guangze Shao, Jitu Xu, Chencheng Hu, Wenyao Jia, Xitong Xu, Yue Gu, Luming Zhang, Zhihuang Zheng , Jiayan Zhong, Siqi Zhu, Shenghao Meng, Zhonghua Zhao, Zhigang Zhang, Jun Liu*, Yanyong Xu* and Huijuan Wu*. Podocyte YAP ablation decreases podocyte adhesion and exacerbates FSGS progression through α3β1 integrin. J Pathol. 2025 Jan;265(1):84-98. doi: 10.1002/path.6370.
2. Xuguang Yang , Bo Deng , Weiwei Zhao, Yangyang Guo, Yaqi Wan , Zhihao Wu , Sheng Su, Jingyan Gu, Xiaoqian Hu, Wenxue Feng, Chencheng Hu, Jia Li, Yanyong Xu*, Xiaowu Huang*, Yuli Lin* FABP5+ lipid-loaded macrophages process tumor-derived unsaturated fatty acid signal to suppress T-cell antitumor immunity. J Hepatol. 2024 Sep 30:S01688278(24)02569-8.doi: 10.1016/j.jhep.2024.09.029.
3. Shuwei Hu# *, Rui Li #, Dongxu Gong #, Pei Hu #, Jitu Xu , Yingjie Ai, Xiaojie Zhao, Chencheng Hu, Minghuan Xu, Chenxi Liu, Shuyu Chen, Jie Fan, Zhonghua Zhao, Zhigang Zhang, Huijuan Wu*, and Yanyong Xu*. Atf3-mediated metabolic reprogramming in hepatic macrophage orchestrates metabolic dysfunction-associated steatohepatitis. Science Advances. 2024 Jul 26;10(30):eado3141. doi: 10.1126/sciadv.ado3141. Epub 2024 Jul 24.
4. Shuwei Hu# , Yingdong Zhu# , Xiaojie Zhao# , Rui Li, Guangze Shao, Dongxu Gong, Chencheng Hu, Hongjun Liu, Kexin Xu, Chenxi Liu, Minghuan Xu, Zhonghua Zhao, Tao Li, Zhigang Hu, Mengle Shao, Jun Liu, Xinwei Li, Huijuan Wu, Jing Li*, and Yanyong Xu*. Hepatocytic Lipocalin-2 Regulates HDL Metabolism and Atherosclerosis via Nedd4-1-SR-BI Axis.Developmental Cell. 2023 Nov 6;58(21):2326-2337.e5. doi: 10.1016/j.devcel.2023.09.007. Epub 2023 Oct 19.
5. Zhiyuan Fang#, Yanyong Xu#, Guowen Liu#, Qi Shao, Xiaodi Niu, Wenjun Tai, Taiyu Shen, Minghe Fan, Meng Chen, Lin Lei, Wenwen Gao, Yuxiang Song, Zhe Wang, Xiliang Du, Xinwei Li. Narirutin activates TFEB (transcription factor EB) to protect against acetaminophen-induced liver injury by targeting PPP3/calcineurin. Autophagy，2023 Feb 13. doi: 10.1080/15548627.2023.2179781.
6. Yanyong Xu#*, Shuwei Hu#, Kavita Jadhav, Yingdong Zhu, Xiaoli Pan, Liya Yin, Yanqiao Zhang*. Hepatocytic Activating Transcription Factor 3 Protects Against Steatohepatitis Via Hepatocyte Nuclear Factor 4α. Diabetes, 2021 Nov;70:2506-25172021.