陈舌

陈舌

shechen@fudan.edu.cn

复旦大学基础医学院生物化学与分子生物学系

卫生部糖复合物重点实验室

代表性论文（*通讯作者）

1. Xiao, Y.#, Hu, J.#, Chen, R., Xu, Y., Pan, B., Gao, Y., Deng, Y., Li, W., Kan, H.*, Chen, S.* (2024) Impact of fine particulate matter on liver injury: evidence from human, mice and cells. J Hazard Mater 469, 133958

2. Wang, B., Zhao, Y., Li, Y., Xu, Y., Chen, Y., Jiang, Q., Yao, D., Zhang, L., Hu, X., Fu, C., Zhang, S. and Chen S*. A plasma SNORD33 signature predicts platinum benefit in metastatic triple-negative breast cancer patients. Mol Cancer. 2022 Jan 18;21(1):22.

3. Zhao, Y., Peng, H., Liang, L., Li, Y., Hu, X., Wang, B., Xu, Y. and Chen S*. Polarity protein Par3 sensitizes breast cancer to paclitaxel by promoting cell cycle arrest. Breast Cancer Res Treat. 2022 Jan DOI: 10.1007/s10549-021-06490-3.

4. Wang, S., Cai, J., Zhang, S., Dong, M., Zhang, L., Xu, Y., Shen, B. and Chen S*. Loss of polarity protein Par3, via transcription factor Snail, promotes bladder cancer metastasis. Cancer Sci. 2021 Jul;112(7):2625-2641. 

5. Wang, X. X., Zhang, S., Dong, P. P., Li, Y. H., Zhang, L., Shi, S. H., Yu, Z. Q. and Chen S*. MRCKbeta links Dasm1 to actin rearrangements to promote dendrite development. J Biol Chem. 2021 Apr 29:100730.

6. Dong P, Wang X, Liu L, Tang W, Ma L, Zeng W, Sun S, Zhang L, Zhang N, Shen S, Janssen H, Dong L, Zhang S, Chen S*. Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma. J Hepatol. 2020 Jun 28;S0168-8278(20)30400-1.

7. Zhao GX, Xu YY, Weng SQ, Zhang S, Chen Y, Shen XZ, Dong L, Chen S*. CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation. Oncogene 2019 Jun;38(23):4574-4589. 

8. Dong P, Ma L, Liu L, Zhao G, Zhang S, Dong L, Xue R, Chen S*. CD86+/CD206+, Diametrically Polarized Tumor-Associated Macrophages, Predict Hepatocellular Carcinoma Patient Prognosis. Int. J. Mol. Sci. 2016, 17(3), 320. 

9. Chen S*, Chen J, Shi H, Wei M, Castaneda-Castellanos DR, Bultje RS,Pei X, Kriegstein AR, Zhang MJ and Shi SH*. Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity. Dev Cell 2013;24(1):26-40 (cover article)

10. Brown K, Chen S, Han Z, Lu CH, Tan X, Ding L, Zhang XJ, Cruz A, Saur D, Anderson S, Huang K, and Shi SH. Clonal Production and Organization of Inhibitory Interneurons in the Neocortex. Science. 2011; 334(6055):480-6.