2022年代表性文章

1. Ying-Ying Guo, Bai-Yu Li, Gang Xiao, Yang Liu, Liang Guo, Qi-Qun Tang*. Cdo1 promotes PPARγ-mediated adipose tissue lipolysis in male mice. Nat Metab. 2022 Oct; 4(10):1352-1368.

2. Weiwei Jin, Guanghui Jiang, Yanbo Yang, Jianye Yang, Wenqian Yang, Dongyang Wang, Xiaohui Niu, Rong Zhong*, Zhao Zhang*, Jing Gong*. Animal-eRNAdb: a comprehensive animal enhancer RNA database. Nucleic Acids Research. 2022 Jan 7; 50(D1):D46-D53.

3. Giannareas N, Zhang Q, Yang X, Na R, Tian Y, Yang Y, Ruan X, Huang D, Yang X, Wang C, Zhang P, Manninen A, Wang L, Wei GH*. Extensive germline-somatic interplay contributes to prostate cancer progression through HNF1B co-option of TMPRSS2-ERG. Nat Commun. 2022;13(1):7320.

4. Yaqiong Chen, Jiang Wang, Yibing Wang, Pengfei Wang, Zan Zhou, Rong Wu, Qian Xu5, Hanyun You, Yaxin Liu, Lei Wang, Lingqin Zhou, Yuting Wu, Lihong Hu, Hong Liu，Yi Liu*. A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex. Nature Communications. 2022; 13(1):246.

5. Zhang N, Huang D, Jiang G, Chen S, Ruan X, Chen H, Huang J, Liu A, Zhang W, Lin X, Wu Y, Zhang Q, Li J, Tsu JH*, Wei GH*, Na R*. Genome-Wide 3'-UTR Single Nucleotide Polymorphism Association Study Identifies Significant Prostate Cancer Risk-Associated Functional Loci at 8p21.2 in Chinese Population. Adv Sci (Weinh). 2022;9(23):e2201420.

6. Zhao Zhang*, Mei Luo, Yuan Liu, Charles Lussier, Jian Zhang, Youqiong Ye, An-Yuan Guo*, Leng Han*. Genetic, Pharmacogenomic, and Immune Landscapes of Enhancer RNAs Across Human Cancers. Cancer Research. 2022, 82(5):785-790.

7. Xinchao Zhang, Shuyan Li, Jing He, Yun-jie Jin, Ruonan Zhang, Wenjing Dong, Mingen Lin, Yajing Yang, Tongguan Tian, Yuefan Zhou, Yixin Xu, Qun-Ying Lei, Jing Zhang, Qing Zhang, Yanping Xu*, Lei Lv*. TET2 suppresses VHL-deficiency-driven clear cell renal cell carcinoma by targeting HIF signaling. Cancer Research. 2022 Jun 6; 82(11):2097-2109.

8. Ruonan Zhang, Yajing Yang, Wenjing Dong, Mingen Lin, Jing He, Xinchao Zhang, Tongguan Tian, Yunlong Yang, Kun Chen, Qun-Ying Lei, Song Zhang*, Yanping Xu*, Lei Lv*. D-mannose facilitates immunotherapy and radiotherapy of triple-negative breast cancer via degradation of PD-L1. Proc Natl Acad Sci. 2022 Feb 22;119(8): e2114851119.

9. Mengfang Wu, Tian Xia, Yaran Li, Tianfa Wang, Shijia Yang, Jinchao Yu, Qiaoyan Liang, Teng Shen*, Min Yu*, Bing Zhao*. Design and fabrication of r-hirudin loaded dissolving microneedle patch for minimally invasive and long-term treatment of thromboembolic disease. Asian Journal of Pharmaceutical Sciences.  2022;17 (2) 284-297.

10. Hao L, Ma J, Wu F, Ma X, Qian M, Sheng W, Yan T, Tang N, Jiang X, Zhang B, Xiao D, Qian Y, Zhang J, Jiang N, Zhou W, Chen W, Ma D*, Huang G*. WDR62 variants contribute to congenital heart disease by inhibiting cardiomyocyte proliferation.Clin Transl Med. 2022;12(7):e941.

11. Meng Ding, Yin-Jun Ma, Ruo-Qi Du, Wei-Yu Zhou, Xin Dou, Qi-Qi Yang, Yan Tang, Shu-Wen Qian, Yun Liu, Dong-Ning Pan, Qi-Qun Tang*, Yang Liu*. CHCHD10 Modulates Thermogenesis of Adipocytes by Regulating Lipolysis. Diabetes. 2022 Sep 1;71(9):1862-1879.

12. Daochuan He, Mengqian Chen, Lei Chang, Jianxin Gu, Fenglin Liu*, Xiaodong Gao*, Yuanyuan Ruan*. De novo pyrimidine synthesis fuels glycolysis and confers chemoresistance in gastric cancer. Cancer Lett. 2022 Jul; 549:215837.

13. Y. Li^#, Y. Deng^#, Y. Zhao, W. Zhang, S. Zhang, L. Zhang, B. Wang, Y. Xu*, S. Chen*. Immunoglobulin Superfamily 9 (Igsf9) Is Trans-Activated by P53, Inhibits Breast Cancer Metastasis Via Fak. Oncogene 2022, 41: 4658-72.

14. B. Wang^#, Y. Zhao^#, Y. Li^#, Y. Xu^#, Y. Chen, Q. Jiang, D. Yao, L. Zhang, X. Hu*, C. Fu*, S. Zhang*, S. Chen*. A Plasma Snord33 Signature Predicts Platinum Benefit in Metastatic Triple-Negative Breast Cancer Patients. Mol Cancer 2022, 21(1): 22.

15. Yan S, Zeng H, Jin K, Shao F, Liu Z, Chang Y, Wang Y, Zhu Y, Wang Z*, Xu L *, Xu J*. NKG2A and PD-L1 expression panel predicts clinical benefits from adjuvant chemotherapy and PD-L1 blockade in muscle-invasive bladder cancer.J Immunother Cancer.2022; 10(5):e004569.

16. Xu Y, Zeng H, Jin K, Liu Z, Zhu Y, Xu L, Wang Z*, Chang Y*, Xu J*. Immunosuppressive tumor-associated macrophages expressing interlukin-10 conferred poor prognosis and therapeutic vulnerability in patients with muscle-invasive bladder cancer. J Immunother Cancer. 2022; 10(3):e003416.

17. Liu Z, Jin K, Zeng H, Shao F, Chang Y, Wang Y, Xu L, Wang Z*, Cui X*,Zhu Y*, Xu J*. B7-H4 correlates with clinical outcome and immunotherapeutic benefit in muscle-invasive bladder cancer. Eur J Cancer. 2022; 171:133-142.

18. Cao Y, He H, Li R, Liu X, Chen Y, Qi Y, Yu K, Wang J, Chen L, Zhang P, Lin C, Liu H, Zhang H, Li H, Shen Z, Huang H, Sun Y, Zhang W*, Qin J*, Xu J*. Latency-associated peptide identifies immunoevasive subtype gastric cancer with poor prognosis and inferior chemotherapeutic responsiveness. Ann Surg. 2022; 275(1): e163–e173.

19. Zhang P, Gu Y, Fang H, Cao Y, Wang J, Liu H, Zhang H, Li H, He H, Li R*, Lin C*, Xu J*. Intratumoral IL-1R1 expression delineates a distinctive molecular subset with therapeutic resistance in patients with gastric cancer.J Immunother Cancer. 2022; 10(2): e004047.

20. Yu K, Gu Y, Zhang P, Fang H, Cao Y, Wang J, Lin C, Liu H, Zhang H, He H, Li R*, Qin J*, Li H*, Xu J*. Intratumoral PD-1⁺CD8⁺ T cells associate poor clinical outcomes and adjuvant chemotherapeutic benefit in gastric cancer. Br J Cancer. 2022; 127(9):1709-1717.

21. Can Li^#, Fenglin Liu^#, Xu Yang^#, Bao Guo, Guoyun Li, Jie Yin, Gaofei He, Caiting Yang, Ling Xu, Shuxuan Li, Hao Wu, Hai Liu, Yuanyuan Ruan, Jianxin Gu, Lan Wang*. Targeting lectin-like oxidized low-density lipoprotein receptor-1 triggers autophagic program in esophageal cancer. Cell Death& Differentiation. 2022 Apr;29(4):697-708.

22. Chen Yufei, Fu Wanrong, Zheng Yunbo, Yang Jing, Liu Yangyang, Qi Zhiyong, Wu Meiling, Fan Zhichao, Yin Kanhua, Chen Yunfeng, Gao Wen, Ding Zhongren, Dong Jianzeng, Li Qi*, Zhang Si*, Hu Liang*. Galectin 3 enhances platelet aggregation and thrombosis via Dectin-1 activa tion: a translational study. European Heart Journal. 2022 Oct 7, 43(37):3556-3574.

23. Yuanyan Wei#, Qihang Chen#, Sijing Huang#, Yinchao Liu#, Yinan Li, Yang Xing, Danfang Shi, Wenlong Xu, Weitao Liu, Zhi Ji, Bingrui Wu, Xiaoning Chen, Jianhai Jiang*. The Interaction between DNMT1 and High-Mannose CD133 Maintains the Slow-Cycling State and Tumorigenic Potential of Glioma Stem Cell. Advanced Science. 2022 Sep, 9(26):e2202216.

24. Han, Jing#; Zhou, Zhuochao#; Zhang, Rongrong#; You, Yijun; Guo, Zizhen; Huang, Jinyan; Wang, Fan; Sun, Yue; Liu, Honglei; Cheng, Xiaobing; Su, Yutong; Shi, Hui; Hu, Qiongyi; Teng, Jialin; Ya ng, Chengde*; Ren, Shifang*; Ye, Junna*. Fucosylation of anti-dsDNA IgG1 correlates with disease ac tivity of treatment-naïve systemic lupus erythematosus patients., EBioMedicine, 2022, 77: 0-10388.