2024年代表性文章

1. Yang Liu ^#, Jing-Jing Jiang ^# ,Shao-Yue Du ^# , Liang-Shan Mu, Jian-Jun Fan, Jun-Chi Hu, Yao Ye, Meng Ding, Wei-Yu Zhou, Qiu-Han Yu, Yi-Fan Xia, Hong-Yu Xu, Yi-Jie Shi, Shu-Wen Qian, Yan Tang, Wei Li, Yong-Jun Dang, Xi Dong, Xiao-Ying Li, Cong-Jian Xu, Qi-Qun Tang*. Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction. Science. 2024 Jun 14;384(6701):eadk5382.

2. Lian C, Zhang C, Tian P, Tan Q, Wei Y, Wang Z, Zhang Q, Zhang Q, Zhong M, Zhou LQ, Ke X, Zhang H, Zhu Y, Li Z, Cheng J, Wei GH*. Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity. Signal Transduct Target Ther. 2024;9(1):258.

3. Zhong M, Xu W, Tian P, Zhang Q, Wang Z, Liang L, Zhang Q, Yang Y, Lu Y, Wei GH*. An Inherited Allele Confers Prostate Cancer Progression and Drug Resistance via RFX6/HOXA10-Orchestrated TGFβ Signaling. Adv Sci (Weinh). 2024;11(32):e2401492.

4. Cruz SP, Zhang Q, Devarajan R, Paia C, Luo B, Zhang K, Koivusalo S, Qin L, Xia J, Ahtikoski A, Vaarala M, Wenta T, Wei GH*, Manninen A*. Dampened Regulatory Circuitry of TEAD1/ITGA1/ITGA2 Promotes TGFβ1 Signaling to Orchestrate Prostate Cancer Progression. Adv Sci (Weinh). 2024;11(11):e2305547.

5. Q. Li^#, Y. Liu^#, J. Wu^#, Z. Zhu, J. Fan, L. Zhai, Z. Wang, G. Du, L. Zhang, J. Hu, D.K. Ma, J.O. Liu, H. Huang, M. Tan, Y. Dang*, W. Jiang*, P4HA2 hydroxylates SUFU to regulate the paracrine Hedgehog signaling and promote B-cell lymphoma progression, Leukemia, 38 (2024) 1751-1763.

6. Wang N, Shi B, Ding L, Zhang X, Ma X, Guo S, Qiao X, Wang L, Ma D*, Cao J*. FMRP protects breast cancer cells fro.m ferroptosis by promoting SLC7A11 alternative splicing through interacting with hnRNPM.Redox Biol. 2024 Oct 2:77:103382. IF: 10.7.

7. Wenjing Dong#, Mingen Lin#, Ruonan Zhang, Xue Sun, Hongchen Li, Tianshu Liu*, Yanping Xu*, Lei Lv*. d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity. Cancer Letters. 2024 Jun 1:591:216883.

8. Yi-chen. Lin, Jia-kang Ma, Hao-zhe Yuan, Zi-qiang Chen, Xing-yu Xu, Meng-ping Jiang, Jia-liang Zhu, Wei-da Meng, Wen-qing Qiu, Yun Liu*. Integrating Reinforcement Learning and Monte Carlo Tree Search for enhanced neoantigen vaccine design. Brief Bioinform. 2024;25(3):bbae247.

9. Dan-dan Zhang, Dong-xiang Jiang, Li-ping Jiang, Jia-kang Ma, Xiao-bing Wang, Xing-yu Xu, Zi-qiang Chen, Meng-ping Jiang, Wen-jing Ye, Jue Wang, Wei-da Meng, Wen-qing Qiu, Ying-yong Hou, Jing Huang*, Yu-chen Jiao*, Yun Liu*, Zi-hua Liu*. HLA-A(+) tertiary lymphoid structures with reactivated tumor infiltrating lymphocytes are associated with a positive immunotherapy response in esophageal squamous cell carcinoma. Br J Cancer. 2024;131(1):184-195.

10. Tian B, Qiao X, Guo S, Li A, Xu Y, Cao J, Zhang X, Ma D*. Synthesis of β-acids loaded chitosan-sodium tripolyphosphate nanoparticle towards controlled release, antibacterial and anticancer activity. Int J Biol Macromol. 2024 Feb;257(Pt 2):128719.

11. Zhao H, Xiong Y, Zhou Z, Xu Q, Zi Y, Zheng X, Chen S, Xiao X, Gong L, Xu H, Liu L, Lu H, Cui Y, Shao S, Zhang J, Ma J, Zhou Q, Ma D*, Li X*. A hidden proteome encoded by circRNAs in human placentas: Implications for uncovering preeclampsia pathogenesis.Clin Transl Med. 2024 Jul;14(7):e1759.

12. Zi-qiang Chen, Xiao-bing Wang, Ze-lin Jin, Bo-sen Li, Dong-xian Jiang, Yan-qiu Wang, Meng-ping Jiang, Dan-dan Zhang, Pei Yuan, Ya-hui Zhao, Fei-yue Feng, Yi-cheng Lin, Li-ping Jiang, Chen-xi Wang, Wei-da Meng, Wen-jing Ye, Jie Wang, Wen-qing Qiu, Hou-bao Liu, Dan Huang, Ying-yong Hou, Xxue-fei Wang, Yu-chen Jiao*, Jian-ming Ying*, Zhi-hua Liu*, Yun Liu*. Deep learning on tertiary lymphoid structures in hematoxylin-eosin predicts cancer prognosis and immunotherapy response. NPJ Precis Oncol. 2024;8(1):73.

13. Yilin Yang, Mengxiao Wu, Yu Pan, Yue Hua, Xinyu He, Xinyang Li, Jiyong Wang, and Xiaoqing Gan*. WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import. Journal of Cell Biology. 2024；223（6）： e202308013.

14. Qiaoyan Liang, Yajun Hu, Qingyun Yuan, Min Yu*, Huijie Wang*, Bing Zhao*，MET Exon 14 Skipping Mutation Drives Cancer Progression and Recurrence via Activation of SMAD2 Signaling, British Journal of Cancer 2024;130(3):380-393.  

15. Q. Yu^#, Y. Dong^#, X. Wang, C. Su, R. Zhang, W. Xu, S. Jiang*, Y. Dang*, W. Jiang*, Pharmacological induction of MHC-I expression in tumor cells revitalizes T cell anti-tumor immunity, JCI Insight 2024, 9(17):e177788.

16. Hu C, Liu Y, Lin L, Yuan C, Ma D*, Huang Q*. Pathogenic Somatic Mutation of DICER1 and Clinicopathological Features in Nasal Chondromesenchymal Hamartomas: A Series of Nine Cases.Am J Surg Pathol. 2024 May 1;48(5):588-595.

17. Shuwen Qian^#, Chenyang Zhang^#, Yan Tang, Mengyuan Dai, Zhihui He, Hong Ma , Linyuan Wang , Qiqi Yang, Yang Liu, Wei Xu, Zhao Zhang, Qi-Qun Tang*. A single-cell sequence analysis of mouse subcutaneous white adipose tissue reveals dynamic changes during weaning. Commun Biol. 2024 Jun 29;7(1):787.

18. Ruyi Xue, Min Li, Ge Zhang, Wei Zhang, Liping Han, Tao Bo, Haoxuan Zhong, Dingjin Yao, Yiran Deng, She Chen*, Si Zhang*. GSDME-mediated pyroptosis contributes to chemotherapy-induced platelet hyperactivity and thrombotic potential. Blood. 2024 Dec 19;144(25):2652-2665.

19. Zhixue Chen, Wenqing Tang, Nana Feng, Minzhi Lv, Fansheng Meng, Huibin Wu, Yitong Zhao, Huajie Xu, Yuxin Dai, Jindan Xue, Jingya Wang, Anjun Xu, Beilin Zhang, Dejie Chu, Yuqin Li, Dejun Wu*, Ling Dong*, Si Zhang*, Ruyi Xue*. Inactivated vaccines reduce the risk of liver function abnormality in NAFLD patients with COVID-19: a multi-center retrospective study. EBioMedicine. 2024 Jan; 99:104912.

20. Yuanyan Wei#*, Shuting Geng#, Yu Si#, Yuerong Yang#, Qihang Chen, Sijing Huang, Xiaoning Chen, Wenlong Xu, Yinchao Liu*, Jianhai Jiang*. The interaction between Collagen 1 and high mannose type CD133 up-regulates glutamine transporter SLC1A5 to promote the tumorigenesis of glioblastoma stem cells. Adv Sci (Weinh) 2024 Jan;11(3):e2306715.

21. Feng Zhang, Qiuyu Jiang, Jialiang Cai, Fansheng Meng, Wenqing Tang, Zhiyong Liu, Xiahui Lin, Zhiyong Liu, Yi Zhou, Xizhong Shen, Ruyi Xue*, Ling Dong*, Si Zhang*. Activation of NOD1 on tumor-associated macrophages augments CD8+ T cell-mediated antitumor immunity in hepatocellular carcinoma. Science Advances. 2024 Oct 4;10(40):eadp8266.

22. Tao Bo, Chenfei Wang*, Dingjin Yao, Qiuyu Jiang, Yitong Zhao, Feifei Wang, Wei He, Weiyi Xu, Hao Zhou, Ming Li, Si Zhang*, Ruyi Xue*. Efficient gene delivery by multifunctional star poly (β-amino ester)s into difficult-to-transfect macrophages for M1 polarization. Journal of Controlled Release. 2024 Apr;368:157-169.

23. Chenfei Wang*, Wei He, Feifei Wang, Haiyang Yong, Tao Bo, Dingjin Yao, Yitong Zhao, Chaolan Pan, Qiaoyu Cao, Si Zhang*, Ming Li*. Recent progress of non-linear topological structure polymers: synthesis, and gene delivery. Journal of Nanobiotechnology. 2024 Jan 27;22(1):40.

24. Feng Zhang, Wenfeng Liu, Fansheng Meng, Qiuyu Jiang, Wenqing Tang, Zhiyong Liu, Xiahui Lin, Ruyi Xue, Si Zhang*, Ling Dong*. Inhibiting PLA2G7 reverses the immunosuppressive function of intratumoral macrophages and augments immunotherapy response in hepatocellular carcinoma. Journal For Immunotherapy of Cancer. 2024 Jan 25;12(1):e008094.

25. Chaolan Pan, Chenfei Wang*, Yitong Zhao, Tao Bo, Liping Han, Dingjin Yao, Yumeng Wang, Xiaoxiao Wang, Linjing Shi, Anqi Zhao, Qiaoyu Cao, Fuying Chen, Wei He, Ying Ye, Si Zhang*, Ming Li*. Superior COL7A1 and TGM1 gene expression in difficult-to-transfect skin cell mediated by highly branched poly(β-amino esters) through stepwise fractionation. Journal of Controlled Release. 2024 Jun; 370:82-94.

26. Xiao, Y. ^#, J. Hu^#, R. Chen, Y. Xu, B. Pan, Y. Gao, Y. Deng, W. Li, H. Kan*, and S. Chen*. Impact of Fine Particulate Matter on Liver Injury: Evidence from Human, Mice and Cells. J Hazard Mater 2024,469:133958.

27. Zhonghua Li*^#, Qi Du^#, Xiaoxiao Feng^#, Xuezheng Song, Zhenggang Ren, Haojie Lu*, A Versatile One-Step Enzymatic Strategy for Efficient Imaging and Mapping of Tumor-Associated Tn Antigen. J Am Chem Soc. 2024 Jul;146(30):20539-20543.

28. Jin K, Xu J, Su X, Xu Z, Li B, Liu G, Liu H, Wang Y, Zhu Y, Xu L, Zhang W, Liu Z*, Wang Z*, Chang Y*, Xu J*. TP53 disruptive mutation predicts platinum-based chemotherapy and PD-1/PD-L1 blockade response in urothelial carcinoma. J Pathol. 2024;263(2):139-149.

29. Su X, Jin K, Guo Q, Xu Z, Liu Z, Zeng H, Wang Y, Zhu Y, Xu L, Wang Z*, Chang Y*, Xu J*. Integrative score based on CDK6, PD-L1 and TMB predicts response to platinum-based chemotherapy and PD-1/PD-L1 blockade in muscle-invasive bladder cancer. Br J Cancer. 2024; 130 (5): 852–860.

30. Gu Y, Sun M, Fang H, Shao F, Lin C, Liu H, Li H, He H, Li R*, Wang J*, Zhang H*, Xu J*. Impact of clonal TP53 mutations with loss of heterozygosity on adjuvant chemotherapy and immunotherapy in gastric cancer. Br J Cancer. 2024; 131(8):1320-1327.

31. Cao Y, Yu K, Zhang Z, Gu Y, Gu Y, Li W, Zhang W, Shen Z*, Xu J*, Qin J*. Blockade of V-domain immunoglobulin suppressor of T cell activation reprograms tumor-associated macrophages and improves efficacy of PD-1 inhibitor in gastric cancer. Clin Transl Med. 2024; 14:e1578.

32. Xu Z, Liu L, Jiang W, Qiu Y, Zhang B, Cheng J, Luo J, Guo J*, Xu J*. VHL missense mutation delineate aggressive clear cell renal cell carcinoma subtype with favorable immunotherapeutic response. J Immunother Cancer 2024; 12(10): e009963.

33. Qiu Y, Liu L, Jiang W, Xu Z, Wang J, Dai S, Guo J*, Xu J*. NKG2A+ CD8+ T cells infiltration determines immunosuppressive contexture and inferior response to immunotherapy in clear cell renal cell carcinoma. J Immunother Cancer 2024; 12:e008368.