导航
代表性论文

2018年

  1. Yang fan, Fan Yang, Yang Xing, Yinan Li, Xiaoning Chen, Jianhai Jiang, Zhilong Ai, Yuanyan Wei. Mono-ubiquitination of Cancer Stem Cell Marker CD133 at Lysine 848 regulates its Secretion and Promotes Cell Migration [J]. Mol Cell Biol. 2018,38(15): e00024-18 
  2. Chunhong Cui, Xiaoning Chen, Ying Liu, Benjin Cao, Yang Xing, Chanjuan Liu, Fan Yang, Yinan Li, Tianxiao Yang, Lingyang Hua, Mi Tian, Yuanyan Wei, Ye Gong, Jianhai Jiang. β1,4-Galactosyltransferase V activates Notch1 signaling in glioma stem-like cells and promotes their transdifferentiation into endothelial cells [J]. The Journal of biological chemistry, 2018, 293(6): 2219-2230
  3. Zhao Y, Lv F, Chen S, Wang Z, Zhang J, Zhang S, Cao J, Wang L, Cao E, Wang B, Hu X. Caveolin-1 expression predicts efficacy of weekly nab-paclitaxel plus gemcitabine for metastatic breast cancer in the phase II clinical trial. BMC Cancer. 2018;18(1):1019.
  4. Lv B, Ma L, Tang W, Huang P, Yang B, Wang L, Chen S, Gao Q, Zhang S, Xia J. FXR Acts as a Metastasis Suppressor in Intrahepatic Cholangiocarcinoma by Inhibiting IL-6-Induced Epithelial-Mesenchymal Transition. Cell Physiol Biochem. 2018;48(1):158-172. 
  5. Liu X, Xue R, Yang C, Gu J, Chen S*, Zhang S*. Cholestasis-induced bile acid elevates estrogen level via farnesoid X receptor-mediated suppression of the estrogen sulfotransferase SULT1E1. J Biol Chem. 2018;293(33):12759-12769.
  6. Liu WA, Chen S, Li Z, Lee CH, Mirzaa G, Dobyns WB, Ross ME, Zhang J, Shi SH. PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia. Genes Dev. 2018;32(11-12):763-780. 
  7. Yang, Biwei, Meiyi Li, Wenqing Tang, Weixin Liu, Si Zhang, Luonan Chen*, and Jinglin Xia*. "Dynamic network biomarker indicates pulmonary metastasis at the tipping point of hepatocellular carcinoma." Nature communications. 2018; 678: s41467-018-03024-2
  8. Cai Y, Huang G, Ma L, Dong L, Chen S, Shen X, Zhang S, Xue R, Sun D, Zhang S*. Smurf2, an E3 ubiquitin ligase, interacts with PDE4B and attenuates liver fibrosis through miR-132 mediated CTGF inhibition. Biochim Biophys Acta Mol Cell Res. 2018;1865(2):297-308.
  9. Wang J, Li H, Zhang H, Chen Y, Cao Y, Li R, Lin C, Wei Y, Xiang X, Fang H, Zhang H, Gu Y, Liu X, Zhou R, Liu H, He H, Zhang W*, Shen Z*, Qin J*, Xu J*. Intratumoral IL17-producing cells infiltration correlate with anti-tumor immune contexture and improved response to adjuvant chemotherapy in gastric cancer. Ann Oncol. 2018 in press.
  10. Wang J, Liu L, Bai Q, Ou C, Xiong Y, Qu Y, Wang Z, Xia Y, Guo J*, Xu J*. Tumor-infiltrating neutrophils predict therapeutic benefit of tyrosine kinase inhibitors in metastatic renal cell carcinoma. Oncoimmunology. 2018 in press.
  11. Fu Q, Xu L, Wang Y, Jiang Q, Liu Z, Zhang J, Zhou Q, Zeng H, Tong S, Qi Y, Hu B, Fu H, Xie H, Zhou L, Chang Y, Zhu Y, Dai B*, Zhang W*, Xu J*. Tumor-associated macrophage-derived IL-23 interlinks kidney cancer glutamine addiction with immune evasion. Eur Urol. 2018 Oct 4. pii: S0302-2838(18)30718-8. doi: 10.1016/j.eururo.2018.09.030. [Epub ahead of print] .
  12. Jiang Q, Fu Q, Chang Y, Liu Z, Zhang J, Xu L, Zhu Y, Wang Y, Zhang W*, Xu J*. CD19+ Tumor-Infiltrating B Cells Prime CD4+ T Cell Immunity and Predict Platinum-Based Chemotherapy Efficacy in Muscle Invasive Bladder Cancer. Cancer Immunol Immun. 2018 Sep 26. doi: 10.1007/s00262-018-2250-9. [Epub ahead of print].
  13. Lin Z, Liu L, Xia Y, Chen X, Xiong Y, Qu Y, Wang J, Bai Q, Guo J*, Xu J*. Tumor infiltrating CD19+ B lymphocytes predict prognostic and therapeutic benefits in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors. Oncoimmunology. 2018 Aug 6;7(10): e1477461. 
  14. Liu Z, Zhu Y, Xu L, Zhang J, Xie H, Fu H, Zhou Q, Chang Y, Dai B*, Xu J*. Tumor stroma-infiltrating mast cells predict prognosis and adjuvant chemotherapeutic benefits in patients with muscle invasive bladder cancer. Oncoimmunology. 2018 Aug 1;7(9): e1474317.
  15. Fu H, Zhu Y, Wang Y, Liu Z, Zhang J, Fu Q, Dai B, Ye D*, Xu J*. Identification and Validation of Stromal Immunotype Predict Survival and Benefit from Adjuvant Chemotherapy in Patients with Muscle Invasive Bladder Cancer. Clin Cancer Res. 2018 Jul;24(13); 3069–78. 
  16. Wu S, He H, Liu H, Cao Y, Li R, Zhang H, Li H, Shen Z*, Qin J*, Xu J*. C-C motif chemokine 22 predicts postoperative prognosis and adjuvant chemotherapeutic benefits in patients with stage II/III gastric cancer. Oncoimmunology. 2018 May 12;7(6):e1433517. 
  17. Xi W, Wang J, Liu L, Xiong Y, Qu Y, Lin Z, Chen X, Wang Z, Yang Y, Xu J*, Guo J*. Evaluation of Tumor Pseudocapsule Status and its Prognostic Significance in Renal Cell Carcinoma. J Urol. 2018 Apr;199(4):915-920. 
  18. Wei Y, Lin C, Li H, Xu Z, Wang J, Li R, Liu H, Zhang H, He H*, Xu J*. Prognostic value of CXCL13 in postoperative clinical outcome and chemotherapeutic benefits for patients with gastric cancer. Cancer Immunol Immun. 2018 Feb;67(2):261-269. 
  19. Zhang H, Liu H, Shen Z, Lin C, Wang X, Qin J, Qin X, Xu J*, Sun Y*. Tumor infiltrating neutrophils is prognostic and predictive for postoperative adjuvant chemotherapy benefit in patients with gastric cancer. Ann Surg. 2018 Feb;267(2):311-318. 
  20. Wang J, Liu L, Qu Y, Xi W, Xia Y, Bai Q, Xiong Y, Long Q, Xu J*, Guo J*. HLA class I expression predicts prognosis and therapeutic benefits from tyrosine kinase inhibitors in metastatic renal cell carcinoma patients. Cancer Immunol Immun. 2018 Jan;67(1):79-87. 
  21. N. Atkins, Jr., Shifang Ren (co-first author), N. Hatcher, P.W. Burgoon, J.W. Mitchell, J.V. Sweedler, M.U. Gillette, Functional Peptidomics: Stimulus- and Time-of-Day-Specific Peptide Release in the Mammalian Circadian Clock, ACS Chem. Neurosci. 2018, 9(8): 2001-2008. 
  22. Wenjun Qin, Hao Pei, Ruihuan Qin, Ran Zhao, Jing Han, Zejian Zhang, Kuiran Dong*, Shifang Ren*, Jianxin Gu. Alteration of Serum IgG Galactosylation as a Potential Biomarker for Diagnosis of Neuroblastoma. J Cancer. 2018 Feb 25; 9(5): 906-913. 
  23. Ting Zhao, Jie Wu, Xiaohui Liu, Lei Zhang, Gang Chen and Haojie Lu*. Diagnosis of thymic epithelial tumor subtypes by a quantitative proteomic approach[J]. ANALYST, 2018, 143:2491–2500.
  24. Hucong Jiang, Hongrui Yin, Liqi Xie, Ying Zhang, Lei Zhang, Peng-Yuan Yang, Haojie Lu*. A novel triplex isobaric termini labeling quantitative approach for simultaneously supplying three quantitative sources[J]. ANALYTICA CHIMICA ACTA, 2018,1001:70 – 77.
  25. Xiaoqin Zhang, Yuting Zhang, Caiyun Fang*, Lei Zhang, Pengyuan Yang, Changchun Wang and Haojie Lu*. Ultradeep palmitoylomics enabled by dithiodipyridine-functionalized magnetic nanoparticles[J]. ANALYTICAL CHEMISTRY. 2018, 90:6161−6168.
  26. Xiaoqin Zhang, Lei Zhang, Guanghui Ji, Qunying Lei, Caiyun Fang* and Haojie Lu*. Site-specific quantification of protein palmitoylation by cysteine-stable isotope metabolic labeling[J]. ANALYTICAL CHEMISTRY. 2018, 90:10543−10550.
  27. Ying Zhang, Ye Peng, Lijun Yang, Haojie Lu*, Advances in sample preparation strategies for MS-based qualitative and quantitative N-glycomics[J]. TRENDS IN ANALYTICAL CHEMISTRY, 2018, 99:34-46.
  28. Qinghe Tong, Tianyang Yan, Tao Tao, Lei Zhang, Liqi Xie and Haojie Lu*. Reductive amination combining dimethylation for quantitative analysis of early-stage glycated proteins[J]. ANALYTICAL CHEMISTRY. 2018, 90:3752−3758.
  29. Lei Wei, Yan Cai, Lijun Yang, Ying Zhang* and Haojie Lu*. Duplex stable isotope labeling (DuSIL) for simultaneous quantitation and distinction of sialylated and neutral N‑Glycans by MALDI-MS[J]. ANALYTICAL CHEMISTRY. 2018, 90:10442−10449.
  30. Hucong Jiang, Lei Zhang, Ying Zhang, Liqi Xie, Yi Wang and Haojie Lu*. HST-MRM-MS: A novel high-sample-throughput multiple reaction monitoring mass spectrometric method for multiplex absolute quantitation of hepatocellular carcinoma serum biomarker. JOURNAL OF PROTEOME RESEARCH(DOI: 10.1021/acs.jproteome.8b00790).
  31. Jie Zhang, Lei Zhang, Can Li, Caiting Yang, Lili Li, Shushu Song, Hao Wu, Fenglin Liu*, Lan Wang*, Jianxin Gu. LOX-1 is a poor prognostic indicator and induces epithelial-mesenchymal transition and metastasis in pancreatic cancer patients. Cellular Oncology. 2018 Feb;41(1):73-84
  32. Yan Gao, Fuming Yang, Zuopeng Su, Zijian He, Jin Xiao, Yaolin Xu,Xiliang Zha, Fulin Xu, Liying Wang.β1,6 GlcNAc branches-modified protein tyrosine phosphatase Mu attenuates its tyrosine phosphatase activity and promotes glioma cell migration through PLCg-PKC pathways.Biochemical and Biophysical Research Communications 505 (2018) 569-577.

2017年

  1. Liang Hu, Lin Chang, Yan Zhang, Lili Zhai, Shenghui Zhang, Zhiyong Qi, Hongmei Yan, Yan Yan, Xinping Luo, Si Zhang, Yiping Wang, Satya P. Kunapuli, Hongying Ye, Zhongren Ding*.  Platelets Express Activated P2Y12 Receptor in Patients with Diabetes. Circulation. 2017; 136: 817-833
  2. Zhang Y#, Xu YY#, Yao CB, Li JT, Zhao XN, Yang HB, Zhang M, Yin M*, Chen J*, Lei QY*. Acetylation targets HSD17B4 for degradation via CMA pathway in response to estrone. Autophagy 2017;13(3):538-553.
  3. Cao Y, Liu H, Li H, Lin C, Li R, Wu S, Zhang H, He H*, Zhang W*, Xu J*. Association of O6-Methylguanine-DNA Methyltransferase Protein Expression With Postoperative Prognosis and Adjuvant Chemotherapeutic Benefits Among Patients With Stage II or III Gastric Cancer. JAMA Surg. 2017 Nov 15;152(11):e173120. 
  4. Zhu Y, Liu Z, Wang Y, Fu H, Wang Z, Xie H, Zhang J, Li G, Dai B, Xu J*, Ye D*. High CXC chemokine receptor 1 level represents an independent negative prognosticator in non-metastatic clear-cell renal cell carcinoma patients. Oncoimmunology. 2017 Aug 8;6(11):e1359450. 
  5. Wang J, Lin C, Li H, Li R, Wu Y, Liu H, Zhang H, He H, Zhang W*, Xu J*. Tumor-infiltrating γδT cells predict prognosis and adjuvant chemotherapeutic benefits in patients with gastric cancer. Oncoimmunology. 2017 Jul 24;6(11):e1353858. 
  6. Lin C, Liu H, Zhang H, Cao Y, Li R, Wu S, Li H, He H, Xu J*, Sun Y*. Tryptase expression as a prognostic marker in patients with resected gastric cancer. Br J Surg. 2017 Jul;104(8):1037-1044. 
  7. Liu Y, Liu H, Yang L, Wu Q, Liu W, Fu Q, Zhang W, Zhang H, Xu J*, Gu J*. Loss of N-acetylgalactosaminyltransferase-4 orchestrate oncogenic microRNA-9 in hepatocellular carcinoma. J Biol Chem. 2017 Feb 24;292(8):3186-200. 
  8. Zhou L, Xu L, Chen L, Fu Q, Liu Z, Chang Y, Lin Z*, Xu J*. Tumor infiltrating neutrophils predict benefit from adjuvant chemotherapy in patients with muscle invasive bladder cancer. Oncoimmunology. 2017 Feb 21;6(4):e1293211. 
  9. Ruihuan Qin, Junjie Zhao, Wenjun Qin, Zejian Zhang, Ran Zhao, Jing Han, Yupeng Yang, Lixiao Li, Xuefei Wang*, Shifang Ren* Sun Y, Gu J. Discovery of Non-invasive Glycan Biomarkers for Detection and Surveillance of Gastric Cancer. J Cancer. 2017 Jul 3;8(10): 1908-1916. 
  10. Ting Cao, Lei Zhang, Ying Zhang, Guoquan Yan, Caiyun Fang, Huimin Bao, Haojie Lu *. Site-specific quantification of protein ubiquitination on MS2 fragment ion level via isobaric peptide labeling[J]. ANALYTICAL CHEMISTRY. 2017, 89:11468-11475.
  11. Yi Di, Ying Zhang, Lei Zhang, Tao Tao, Haojie Lu *. MdFDIA: A mass defect based four-plex data-independent acquisition strategy for proteome quantification[J]. ANALYTICAL CHEMISTRY. 2017, 89:10248-10255.
  12. Lijun Yang, Ye Peng, Jing Jiao, Tao Tao, Jun Yao, Ying Zhang *, Haojie Lu *. Metallic element chelated tag labeling (MeCTL) for quantitation of N-Glycans in MALDI-MS[J]. ANALYTICAL CHEMISTRY. 2017, 89:7470-7476.
  13. Shu Zhang, Wei Li, Haojie Lu *, Yinkun Liu. Quantification of N-glycosylation site occupancy status based on labeling/label-free strategies with LC-MS/MS[J]. TALANTA. 2017, 170:509-513.
  14. Cheng Zhang, Tao Tao, Wenjuan Yuan, Lei Zhang, Xiaoqin Zhang, Jun Yao, Ying Zhang *, Haojie Lu *. Fluorous solid-phase extraction technique based on nanographite fluoride[J]. ANALYTICAL CHEMISTRY. 2017, 89:4566-4572.
  15. Zhongjie Wang, Yan Cai, Yi Wang, Xinwen Zhou, Ying Zhang *, Haojie Lu *. Improved MALDI imaging MS analysis of phospholipids using graphene oxide as new matrix[J]. SCIENTIFIC REPORTS. 2017, 7:44466.
  16. Wenjuan Yuan, Ying Zhang, Yun Xiong, Tao Tao, Yi Wang, Jun Yao, Lei Zhang, Guoquan Yan, Huimin Bao, Haojie Lu *. Highly selective and large scale mass spectrometric analysis of 4-Hydroxynonenal modification via fluorous derivatization and fluorous solid-phase extraction[J]. ANALYTICAL CHEMISTRY. 2017, 89:3093-3100.
  17. Yun Xiong, Ying Zhang, Jun Yao, Guoquan Yan, Haojie Lu*. Direct digestion of living cells via a gel-based strategy for mass spectrometric analysis[J]. CHEMISTRY COMMUNICATIONS. 2017, 53:1421-1424.
  18. Li C, Zhang J, Wu H, Li L, Yang C, Song S, Peng P, Shao M, Zhang M, Zhao J, Zhao R, Wu W, Ruan Y, Wang L*, Gu J. Lectin-like oxidized low-density lipoprotein receptor-1 facilitates metastasis of gastric cancer through driving epithelial mesenchymal transition and PI3K/Akt/GSK3 activation. Scientific Reports (SCI, IF=4.259, 3区). 2017 Mar 27;7: 45275.
  19. Yaolin Xu, Ruiqi Chang, Fulin Xu, Yan Gao, Fuming Yang, Can Wang,Jin Xiao,Zuopeng Su, Yongyan Bi, Liying Wang, Xiliang Zha. N-Glycosylation at Asn 402 Stabilizes N-Cadherin and Promotes Cell–Cell Adhesion of Glioma Cells.J Cell Biochem.118:1423–1431 (2017)
  20.  Jin Xiao , Yan Gao , Fuming Yang , Can Wang , Yaolin Xu , Ruiqi Chang ,Xiliang Zha , Liying Wang .β1,6 GlcNAc branches-modified PTPα enhances its stability and promotes focal adhesion formation in MCF-7 cells.Biochem Biophys Res Commun.482 (2017) 1455-1461


2016年

  1. Chanjuan Liu, Yinan Li,Yang Xing, Benjin Cao, Fan Yang, Tianxiao Yang, Zhilong Ai, Yuanyan Wei, and Jianhai Jiang. The Interaction between Cancer Stem Cell Marker CD133 and Src Protein Promotes Focal Adhesion Kinase (FAK) Phosphorylation and Cell Migration [J]. J Biol Chem, 2016, 291(30), 15540 –15550.
  2. Wang J#, Zhu ZH#, Yang HB, Zhang Y, Zhao XN, Zhang M, Liu YB, Xu YY*,Lei QY.  Cullin 3 targets methionine adenosyltransferase IIα for ubiquitylation-mediated degradation and regulates colorectal cancer cell proliferation. FEBS Journal 2016;283(13):2390-402.
  3. Xue R, Tang W, Dong P, Weng S, Ma L, Chen S, Liu T, Shen X, Huang X, Zhang S*, Dong L*. CAPS1 Negatively Regulates Hepatocellular Carcinoma Development through Alteration of Exocytosis-Associated Tumor Microenvironment. Int J Mol Sci. 2016;17(10): pii: E1626.
  4. Ma L, Dong P, Liu L, Gao Q, Duan M, Zhang S, Chen S, Xue R*, Wang X*. Overexpression of protein O-fucosyltransferase 1 accelerates hepatocellular carcinoma progression via the Notch signaling pathway. Biochem Biophys Res Commun. 2016;473(2):503-10.
  5. Dong P, Ma L, Liu L, Zhao G, Zhang S, Dong L, Xue R, Chen S*. CD86+/CD206+, Diametrically Polarized Tumor-Associated Macrophages, Predict Hepatocellular Carcinoma Patient Prognosis Int. J. Mol. Sci. 2016;17(3):320. 
  6. Wang J, Liu L, Qu Y, Xi W, Xia Y, Bai Q, Xiong Y, Long Q, Xu J*, Guo J*. Prognostic value of SETD2 expression in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors. J Urol. 2016 Nov;196(5):1363-1370. 
  7. Zhou L, Chang Y, Xu L, Liu Z, Fu Q, Yang Y, Lin Z*, Xu J*. The presence of vascular mimicry predicts high recurrence risk of clear-cell renal cell carcinoma after radical nephrectomy. J Urol. 2016 Aug;196(2):335-42. 
  8. Shifang Ren, Zejian Zhang, Congjian Xu, Lin Guo, Renquan Lu, Yihong Sun, Jianming Guo, Ruihuan Qin, Wenjun Qin, Jianxin Gu. Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types. Cell Res. 2016 Aug; 26(8): 963-6. 
  9. Ran Zhao, Xiaoxia Liu, Yisheng Wang, Xiaoxiang Jie, Ruihuan Qin, Wenjun Qin, Mengyu Zhang, Haiyan Tai, Caiting Yang, Lili Li, Peike Peng, Miaomiao Shao, Xingwang Zhang, Hao Wu, Yuanyuan Ruan, Congjian Xu*, Shifang Ren*, Jianxin Gu. Integrated glycomic analysis of ovarian cancer side population cells. Clin Proteom. 2016 epubishing. 
  10. Caiyun Fang, Xiaoqin Zhang, Lei Zhang, Xing Gao, Pengyuan Yang, Haojie Lu *. Identification of palmitoylated transitional endoplasmic reticulum ATPase by proteomic technique and pan antipalmitoylation antibody[J]. JOURNAL OF PROTEOME RESEARCH, 2016, 15: 956-962.
  11. Qinghe Tong, Tao Tao, Liqi Xie *, Haojie Lu *. ELISA-PLA: A novel hybrid platform for the rapid, highly sensitive and specific quantification of proteins and post-translational modifications[J].  BIOSENSORS & BIOELECTRONICS, 2016, 80: 385-391.
  12. Tao Tao, Zhixian He, Zhiming Shao *, Haojie Lu *. TAB3 O-GlcNAcylation promotes metastasis of triple negative breast cancer[J]. ONCOTARGET, 2016, 7:22807-22818.
  13. Meng Yu, Yi Di, Ying Zhang, Jia Guo, Haojie Lu *, Changchun Wang *. Fabrication of alkoxyamine-functionalized magnetic core-shell microspheres via reflux precipitation polymerization for glycopeptide enrichment[J]. POLYMERS, 2016, 8: 74. 
  14. Weili Miao, Cheng Zhang, Yan Cai, Ying Zhang *, Haojie Lu *. Fast solid-phase extraction of Nlinked glycopeptides by amine-functionalized mesoporous silica nanoparticles[J]. ANALYST, 2016, 141:2435-2440.
  15. Haojie Lu, Ying Zhang, Pengyuan Yang*. Advancements in mass-spectrometry based glycoproteomics and glycomics. [J]. NATIONAL SCIENCE REVIEW, 2016 ,3: 345–364.
  16. Zhu H#, Fang X#, Zhang D, Wu W, Shao M, Wang L*, Gu J. Membrane-bound heat shock proteins facilitate the uptake of dying cells and cross-presentation of cellular antigen. Apoptosis. 2016 Jan; 21(1):96-109.
  17. Shao M, Li L, Song S, Wu W, Peng P, Yang C, Zhang M, Duan F, Jia D, Zhang J, Wu H, Zhao R, Wang L*, Ruan Y*, Gu J. E3 ubiquitin ligase CHIP interacts with C-type lectin-like receptor CLEC-2 and promotes its ubiquitin-proteasome degradation. Cellular Signalling. 2016 Oct;28(10):1530-6.
  18. Wang L#, Yin J#, Wang X#, Shao M, Duan F, Wu W, Peng P, Jin J, Tang Y, Ruan Y*, Sun Y*, Gu J*. C-type Lectin-like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of PI3K Subunits. Gastroenterology. 2016 May; 150(5):1183-1195.

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