-
Ling Lin, Shuyi Chen, Hua Wang, Bin Gao, Bhaskar Kallakury, Krithika Bhuvaneshwar, Katherine Cahn, Yuriy Gusev, Xue Wang, Yunan Wu, John L. Marshall, Xiuling Zhi*(生理与病理生理学系), Aiwu Ruth He. SPTBN1 inhibits inflammatory responses and hepatocarcinogenesis via the stabilization of SOCS1 and downregulation of p65 in hepatocellular carcinoma. Theranostics. 2021
-
Fei Li, Ming Han, Pengfei Dai, Wei Xu#, Juan He, Xiaoting Tao, Yang Wu#, Xinyuan Tong, Xinyi Xia, Wangxin Guo, Yunjiao Zhou, Yunguang Li, Yiqin Zhu, Xiaoyu Zhang, Zhuang Liu, Rebiguli Aji1, Xia Cai, Yutang Li, Di Qu, Yu Chen, Shibo Jiang, Qiao Wang, Hongbin Ji, Youhua Xie, Yihua Sun, Lu Lu*(病原生物学系), Dong Gao. Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide. Nature Communications. 2021
-
Cong Niu, Siqing Wang, Jieyu Guo, Xiangxiang Wei, Mengping Jia, Zhaoxiong Chen, Wenxuan Gong, Yue Qin, Xinhong Wang, Xiuling Zhi, Meng Lu, Sifeng Chen, Mingxia Gu, Jianyi Zhang, Jingdong J. Han, Fei Lan, Dan Meng*(生理与病理生理学系). BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer-promoter activity and maintains pluripotency. Nucleic Acids Research. 2021
-
Xiaojing Li, Yuanyuan Zhang, Yuhua Fu, Hao Zhang, Hexuan Li, Quanfu Li, Hailing Li, Renke Tan, Chenxiao Jiang, Wei Jiang, Zengxia Li, Cheng Luo, Oun Lu, Yongjun Dang*(生物化学与分子生物学系). Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex. Acta Pharmacologica Sinica. 2021
-
Xiaoting Sun, Xingkang He, Yin Zhang, Kayoko Hosaka, Patrik Andersson, Jing Wu, Jieyu Wu, Xu Jing, Qiqiao Du, Xiaoli Hui, Bo Ding, Ziheng Guo, An Hong, Xuan Liu, Yan Wang, Qing Ji, Rudi Beyaert, Yunlong Yang*(细胞与遗传医学系), Qi Li, Yihai Cao. Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism. Gut. 2021
-
Leilei Shi, Wenbo Wu, Yukun Duan, Li Xu, Sha Li, Xihui Gao*(病原生物学系), Bin Liu. Carrier-Free Hybrid DNA Nanoparticles for Light-Induced Self-Delivery of Functional Nucleic Acid Enzymes. Acs Nano. 2021
-
Chunli Qin, Ji Zhou, Demin Yao, Han Zhuang, Hui Wang, Shiyao Chen, Yonghong Shi, Zhijian Song*(数字医学中心). Vertebrae Labeling via End-to-End Integral Regression Localization and Multi-Label Classification Network. IEEE Transactions On Neural Networks And Learning Systems. 2021
-
Chao Zhang, Yifan Wang, Yuanfei Zhu, Caixuan Liu, Chenjian Gu, Shiqi Xu, Yalei Wang, Yu Zhou, Yanxing Wang, Wenyu Han, Xiaoyu Hong, Yong Yang, Xueyang Zhang, Tingfeng Wang, Cong Xu, Qin Hong, Shutian Wang, Qiaoyu Zhao, Weihua Qiao, Jinkai Zang, Liangliang Kong, Fangfang Wang, Haikun Wang, Di Qu, Dimitri Lavillette, Hong Tang, Qiang Deng, Youhua Xie*(病原生物学系), Yao Cong, Zhong Huang. Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections. Nature Communications. 2021