职 称:副教授
电 话:021-54237526
电子邮箱:jwangf@shmu.edu.cn
办公地点:上海市徐汇区东安路130号西13号楼713
教育经历
工作经历
获得奖项
研究方向
科研项目
代表性论著
1991.09—1996.06 上海医科大学药理专业本科生
2002.09—2005.07 复旦大学中西医结合基础专业硕士研究生
2005.09—2009.12 复旦大学中西医结合基础专业博士研究生
2009.12 — 至今 复旦大学基础医学院中西医结合系,副教授(期间2013.02—2014.02 哈佛大学医学院/Dana-Farber癌症研究所,访问学者)
2000.04 —2009.11 复旦大学基础医学院中西医结合系,讲师(期间2007.01—2008.02 美国威斯康新Blood Research Institute, 访问学者)
1996.07—2000.04 上海医科大学,医学神经生物学国家重点实验室,助教
2010,中国针灸学会科学技术三等奖,中国针灸学会
2016,中西医结合学会科技进步二等奖,中国中西医结合学会
针刺与中药改善神经退行性疾病的神经免疫机制
胶质细胞在脱髓鞘疾病发病中的作用及机制
2020,国家自然科学基金面上项目,“GSDMD细胞焦亡途径调控“疾病相关小胶质细胞(DAM)”表型介导针刺促进髓鞘修复的效应机制”,主持
2017,国家重点研发计划项目,“LED 用于健康与医疗的机理、方法、设备与应用研究”,参加
2013,国家科技部“973”计划项目,“针药复合麻醉机体保护机制研究”,参加
2012,国家自然科学基金青年项目,“miR-124介导的小胶质细胞激活在电针调节创伤应激大鼠免疫功能中的作用及其调控机制”,主持
2010,上海市科委,“中枢小胶质细胞在电针改善急性创伤疼痛时免疫功能紊乱中的作用”,主持
Zou Z, Sun J, Kang Z, Wang Y, Zhao H, Zhu K, Wang J*. Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model. Evid Based Complement Alternat Med. 2020 Jul 4;2020:3205176
Chen Y, Sun JX, Chen WK, Wu GC, Wang YQ, Zhu KY, Wang J*. miR-124/VAMP3 is a novel therapeutic target for mitigation of surgical trauma-induced microglial activation. Signal Transduct Target Ther. 2019 Aug 16;4:27. doi: 10.1038/s41392-019-0061-x.
Zhu K, Sun J, Kang Z, Zou Z, Wu X, Wang Y, Wu G, Harris RA, Wang J*. Repurposing of omeprazole for oligodendrocyte differentiation and remyelination. Brain Res 2019 May 1;1710:33-42
Zhu K, Sun J, Kang Z, Zou Z, Wu G, Wang J*. Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance. Front Neurosci 2017 Jan 10;10:613.
Lou W, Chen Y, Zhu KY, Deng H, Wu T, Wang J*. Polyphyllin I Overcomes EMT-Associated Resistance to Erlotinib in Lung Cancer Cells via IL-6/STAT3 Pathway Inhibition. Biol Pharm Bull. 2017 Aug 1;40(8):1306-1313
Wang J#, Mikse O, Liao RG, Li Y, Tan L, Janne PA, Gray NS, Wong KK, Hammerman PS. Ligand associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3 dependent cancer cells. Oncogene. 2015 Apr 23;34(17):2167-77.
Tan L#, Wang J#(co-first), Tanizaki J, Huang ZF, Aref AR, Rusan M, Zhu SJ, Zhang YY, Ercan D, Liao RG , Capelletti M, Zhou WJ , Hur W , Kim N, Sim T, Gaudet S, Barbie DA, Yeh JJ, Yun CH, Hammerman PS, Mohammadi M, Janne PA, Gray NS. Development of covalent inhibitors that can overcome resistance to first generation FGFR kinase inhibitors. Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):E4869-77
Tian GX, Zhu XQ, Chen Y, Wu GC and Wang J*. Huperzine A inhibits CCL2 production in experimental autoimmune encephalomyelitis mice and in cultured astrocyte. Int J Immunopathol Pharmacol, 2013,26(3): p. 757-64.
Wang J#*, Chen F, Zheng P, Deng W, Yuan J, Peng B, Wang R, Liu W, Zhao H, Wang Y and Wu G. Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in mice. Exp Neurol, 2012, 236(1): p. 79-87.
Wang J#, Zhao H, Cao XD: Neuroimmuno-effect of acupuncture on immune-mediated disorders, (Editors: Ying Xia, Xiaoding Cao, Gencheng Wu, Jieshi Cheng, Acupuncture therapy for neurological diseases: A neurobiological view). TSINGHUA and Springer; 1st Edition 2010, pp365-388(英文专著)