高西辉

  • 职    称:青年研究员,博士生导师

  • 电子邮箱:gaoxihui@fudan.edu.cn

  • 办公地点:复星楼207

  • 教育经历

  • 工作经历

  • 获得人才项目

  • 获得奖项

  • 研究方向

  • 科研项目

  • 课程讲授

  • 学术兼职

  • 代表性论著

  • 2014.09-2017.07    复旦大学药学院             药剂学博士

  • 2011.09-2014.07    复旦大学药学院             药剂学硕士

  • 2006.09-2010.07    山东大学药学院             药学学士

  • 2019.07-至今  复旦大学基础医学院,病原生物学系,青年研究员

  • Biomaterials Science 2021年度Emerging Investigators;

  • 上海市青年科技启明星人才计划;

  • 中国博士后创新人才支持计划。

  • 上海市浦东新区优秀科技论文一等奖;

  • 国际脑血流与脑代谢大会青年学者旅行奖,德国柏林。

  • 抗感染、抗肿瘤药物/核酸递送载体开发;

  • 基因/化学工程化溶瘤病毒开发。

  • 主持国家自然科学基金面上项目、国家自然科学基金青年项目、上海市青年科技启明星、上海市重大传染病专项子任务、复旦大学引进人才项目、复旦大学争优人才培养计划、中国博士后创新人才支持计划、中国博士后基金等多项科研项目。

  • 医学微生物学、医药中的同位素技术、细胞微生物学。

  • 国际脑血流与脑代谢学会会员;

  • 国际分子影像学会会员;

  • 中国生物医学工程学会会员;

  1. Xihui Gao#, Sha Li#, Fei Ding, Xinlong Liu, Yijing Wu, Jing Li, Jing Feng*, Xinyuan Zhu, Chuan Zhang*. Virus‐mimicking nucleic acid nanogel reprograms the microglia and macrophage for glioblastoma therapy. Adv. Mater., 2021, 33, 2006116. (IF: 30.849)

  2. Xihui Gao#, Qi Yue#, Zining Liu, Mengjing Ke, Xingyu Zhou, Sihan Li, Jianping Zhang, Ren Zhang, Ying Mao and Cong Li*, Guiding brain tumor surgery via blood brain barrier permeable gold nanoprobes with acid triggered MRI/SERRS signal. Adv. Mater., 2017, 29, 1603917. (IF: 30.849)

  3. Xihui Gao#, Sha Li#, Fei Ding, Hongjia Fan, Leilei Shi, Lijuan Zhu, Jing Li, Jing Feng*, Xinyuan Zhu, Chuan Zhang*, Rapid detection of exosomal microRNAs using virus-mimicking fusogenic vesicles. Angew. Chem. Int. Ed. Engl. 2019, 58, 8719-8723. (IF: 15.336)

  4. Xihui Gao, Junqiang Ding, Chongbing Liao, Jinliang Xu, Xiaoxiao Liu, Wuyuan Lu*. Defensins: the natural peptide antibiotic. Adv. Drug Deliv. Rev., 2021: 114008. (IF: 15.470)

  5. Leilei Shi, Wenbo Wu, Yukun Duan, Li Xu, Sha Li, Xihui Gao*, and Bin Liu*. Carrier-free hybrid DNA nanoparticles for light-induced self-delivery of functional nucleic acid enzymes. ACS Nano 2021, 15, 1841–1849. (co-corresponding author, IF: 15.881)

  6. Xihui Gao, Jun Qian, Shuyan Zheng, Yinzhi Changyi, Jianping Zhang, Shenghong Ju*, Jianhua Zhu, Cong Li*, Overcoming the blood–brain barrier for delivering drugs into the brain by using adenosine receptor nanoagonist. ACS Nano 2014, 8, 3678-3689. (IF= 15.881)

  7. Jiapei Yang#, Lei Wang#, Yue Su#, Lingyue Shen, Xihui Gao*, Leilei Shi*, Xinyuan Zhu*, Color-convertible fluorescent nanoprobe for Parkinson disease diagnosis. Chem. Eng. J. 2021, 33, 15, 5974–5980. (co-corresponding author, IF: 13.273)

  8. Xihui Gao#,Qi Yue#,Yikang Liu,Dandan Fan,Kun Fan,Sihan Li,Jun Qian,Limei Han,Fang Fang, Fulin Xu, Daoying Geng, Liang Chen*, Xin Zhou, Ying Mao, and Cong Li*, Image-guided chemotherapy with specifically tuned blood brain barrier permeability in glioma margins. Theranostics 2018, 8, 3126. (IF= 11.556)

  9. Xihui Gao#, Junqiang Ding#, Qianqian Long#, Changyou Zhan*. Virus-mimetic systems for cancer diagnosis and therapy. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol., 2021, e1692. (IF: 9.182)

  10. Sha Li#, Jinliang Xu#, Jun Qian, Xihui Gao*. Engineering extracellular vesicles for cancer diagnosis and therapy: recent advances and challenges in clinical translation. Biomater. Sci., 2020, 8, 6978-6991. (IF: 6.843)

  11. Huihui Yan#, Xihui Gao#, Yunfei Zhang, Wenju Chang, Jianhui Li, Xinwei Li, Qin Du, Cong Li, Imaging tiny hepatic tumor xenografts via endoglin-targeted paramagnetic/optical nanoprobe. ACS Appl. Mater. Interfaces, 2018, 10, 17047-17057. (co-first author, IF= 9.229)

  12. Sha Li, Yijing Wu, Fei Ding, Jiapei Yang, Jing Li, Xihui Gao*, Chuan Zhang*, Jing Feng*. Engineering macrophage-derived exosomes for targeted chemotherapy of triple-negative breast cancer. Nanoscale, 2020, 12, 10854-10862. (co-corresponding author, IF: 7.790)

  13. Han Xue, Fei Ding, Jiao Zhang, Yuanyuan Guo, Xihui Gao*, Jing Feng, Xinyuan Zhu and Chuan Zhang*. DNA tetrahedron-based nanogels for siRNA delivery and gene silencing. Chem. Commun., 2019, 55, 4222-4225. (co-corresponding author, IF= 6.222)

  14. Xihui Gao#, Yuancheng Wang#, Yikang Liu, Qi Yue, Zining Liu, Mengjing Ke, Shengyuan Zhao, Cong Li*, Nanoagonist-mediated endothelial tight junction opening: A strategy for safely increasing brain drug delivery in mice. J. Cereb. Blood Flow Metab. 2017, 37, 1410-1424. (IF= 6.200)