职 称:副教授
电子邮箱:zhuangtao5217@163.com
办公地点:西七号楼217室
教育经历
工作经历
获得人才项目
研究方向
科研项目
讲授课程
代表性论著
代表性专利
2013. 09-2017. 05 同济大学内科学博士研究生
2010. 09-2013. 07 同济大学病原生物学硕士研究生
2006. 09-2010. 07 山东师范大学生物技术本科生
2023. 12-至今 复旦大学基础医学院副教授
2021. 01-2023. 12 复旦大学基础医学院青年副研究员
2017. 12-2020. 12 同济大学博士后
2022,卫生健康青年人才,上海市卫健委
2021,上海市启明星,上海市科委
方向一 内皮细胞参与心血管稳态失衡的调控机制
方向二 免疫调控心血管稳态失衡的作用和机制
方向三 肝脏分泌因子调控心血管稳态失衡的作用和机制
温度调节温度调控淋巴管影响动脉粥样硬化的机制研究,国家自然科学基金面上项目(82470472),2025.01-2028.12,主持
内皮细胞与心血管疾病,复旦大学卓学项目,2023.06-2025.05
内皮细胞基质蛋白CCN5调控流体介导的动脉粥样硬化的作用与机制,国家自然科学基金面上项目基金(8207021066),2021.01-2024.12 主持
内皮细胞基质蛋白CCN5调控动脉粥样硬化的作用与机制,上海市科学技术委员会启明星项目(21QA1401400), 2021.07 -2024.06, 主持
平滑肌细胞Gata6-CCN5信号通路在血管损伤后内膜增生过程中的作用机制研究,国家自然科学基金青年基金(81800253),2019.1-2021.12, 主持
功能学科综合实验,生理学,高级生理学实验
Tao Zhuang †; Mei-Hua Chen †; Ruo-Xi Wu; Jing Wang; Xi-De Hu; Ting Meng; Ai-Hua Wu; Yan Li; Yong-Feng Yang; Yu Lei; Dong-Hua Hu; Yan-Xiu Li; Li Zhang; Ai-Jun Sun; Wei Lu*; Guan-Nan Zhang*; Jun-Li Zuo*; Cheng-Chao Ruan* ; ALKBH5-mediated m6A modification of IL-11 drives macrophage-to- myofibroblast transition and pathological cardiac fibrosis in mice, Nature Communications, 2024
Tao Zhuang †; Yu Lei †; Jin-Jia Chang †; Yan-Ping Zhou †; Yan Li; Yan-Xiu Li; Yong-Feng Yang; Mei-Hua Chen; Ting Meng; Shi-Man Fu; Li-Hao Huang; Wai-San Cheang; John P Cooke*; Zhi-Hui Dong*; Ying-Nan Bai*; Cheng-Chao Ruan* ; A2AR-mediated lymphangiogenesis via VEGFR2 signaling prevents salt-sensitive hypertension, European Heart Journal, 2023, 44(29): 2730-2742
Wenrun Wu †; Wenzhen Bao †; Xiaoli Chen †; Yushi Lu; Ji Fang; Jiwen Liu; Sheng Peng; Jingjiang Pi; Brian Tomlinson; Paul Chan; Qi Zhang; Lin Zhang; Zhongmin Liu; Jie Liu*; Yuzhen Zhang*; Tao Zhuang* ; Endothelial Gata6 deletion reduces monocyte recruitment and proinflammatory macrophage formation and attenuates atherosclerosis through Cmpk2-Nlrp3 pathways, Redox Biology, 2023, 64: 102775
Tao Zhuang†, Jie Liu†, Xiaoli Chen†, Lin Zhang, et al. Endothelial Foxp1 suppresses atherosclerosis via modulation of Nlrp3 inflammasome activation. Circulation Research. 2019 Aug 30;125(6).
Jie Liu†, Tao Zhuang†, Jingjiang Pi†, Xiaoli Chen, et al. Endothelial Foxp1 regulates pathological cardiac remodeling through TGF-β1-endothelin-1 signal pathway. Circulation. 2019 Aug 20;140(8). (Co-first author).
Tao Zhuang†, Jie Liu†, Xiaoli Chen†, Jingjiang Pi, et al. Cell-Specific Effects of GATA (GATA Zinc Finger Transcription Factor Family)-6 in Vascular Smooth Muscle and Endothelial Cells on Vascular Injury Neointimal Formation. Arterioscler Thromb Vasc Biol. 2019 May;39(5):888-901.
Jingjiang Pi†, Jie Liu†, Tao Zhuang†, Lin Zhang et al. Elevated expression of miRNA 302-367 in endothelial cells inhibits developmental angiogenesis via cdc42/ccnd1 mediated signaling pathways. Theranostics. 2018, Vol. 8, Issue 6. (Co-first author).
Jingjiang Pi†, Ting Tao†, Tao Zhuang†, Huimin Sun, et al. A microRNA302-367-Erk1/2-Klf2-S1pr1 Pathway Prevents Tumor Growth via Restricting Angiogenesis and Improving Vascular Stability. Circulation Research. 2017 Jan 6;120(1):85-98.(Co-first author).
基质细胞蛋白 CCN5 组合物及其应用,202011163644.4, 202011,本人排名 2
miRNA302-367 簇的微小RNA在靶向抑制血管新生和肿瘤生长的应用,P2016-1610-1CNCN,201610,本人排名5