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Yuli Lin#, Liuling Xiao, Qian Cai, Cuisong Zhu, Shufen Li, Bingji Li, Ting Liu, Qiongyue Zhang, Yi Wang, Yiming Li, Xing He, Dongning Pan, Qiqun Tang, Xiaohui Wu, Weiqing Pan, Jiqiu Wang, Xi Li, Rui He*(免疫学系). The chemerin-CMKLR1 axis limits thermogenesis bycontrolling a beige adipocyte/IL-33/type 2 innate immunity circuit. Science Immunology. 2021
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Shuai Xia, Qiaoshuai Lan, Yun Zhu, Chao Wang, Wei Xu, Yutang Li, Lijue Wang, Fanke Jiao, Jie Zhou, Chen Hua, Qian Wang, Xia Cai, Yang Wu, Jie Gao, Huan Liu, Ge Sun, Jan Münch, Frank Kirchhoff, Zhenghong Yuan, Youhua Xie, Fei Sun, Shibo Jiang* & Lu Lu*(病原生物学系). Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation. Signal Transduction And Targeted Therapy. 2021
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Meng Qiu, Yanhong Duo, Weiyuan Liang, Yunlong Yang#(细胞与遗传学系), Bin Zhang, Zhongjian Xie, Xiaoli Yang, Guiqing Wang, Ni Xie, Guohui Nie, Omar A Alhartomy, Ahmed A ALGhamdi, Swelm Wageh, Yihai Cao, Han Zhang. Nanopoxia: Targeting Cancer Hypoxia by Antimonene-Based Nanoplatform for Precision Cancer Therapy. Advanced Functional Materials. 2021
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Sun Nannan, Xie Qiong, Dang Yongjun*(生物化学与分子生物学系), Wang Yonghui. Agonist Lock Touched and Untouched Retinoic Acid Receptor-Related Orphan Receptor-γt (RORγt) Inverse Agonists: Classification Based on the Molecular Mechanisms of Action. Journal Of Medicinal Chemistry. 2021
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Wang Chao, Wang Xinling, Wang Huan, Pu Jing, Li Qing, Li Jiahui, Liu Yang, Lu Lu*, Jiang Shibo*(病原生物学系). A Two-Birds-One-Stone Approach toward the Design of Bifunctional Human Immunodeficiency Virus Type 1 Entry Inhibitors Targeting the CCR5 Coreceptor and gp41 N-Terminal Heptad Repeat Region. Journal Of Medicinal Chemistry. 2021
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Yujia Jin, Diao Yu, Xiaolong Tian, Huixian Li, Xiaochao Zhou, Yu Kong, Wei Zhang, Lu Zhang, Cheng Lei, Zhenlin Yang, Chao Tu, Yanling Wu* & Tianlei Ying*(病原生物学系). A novel and effective approach to generate germline-like monoclonal antibodies by integration of phage and mammalian cell display platforms. Acta Pharmacologica Sinica. 2021
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Linyu Yan, Weiwei Jin, Qingwen Zhao, Xuan Cui, Ting Shi, Yingjiang Xu, Feiyan Li, Wenfang Jin, Zhe Zhang, Zhao Zhang, QiQun Tang, Dongning Pan*(生物化学与分子生物学系). PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex. Advanced Science. 2021
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Yang Chengbin, Xu Chenyue, Li Zhipeng, Chen Yi, Wu Tianze, Hong Hui, Lu Mingzhu, Jia Yu, Yang Yongtai, Liu Xiaofeng, Deng Mingli, Chen Zhenxia, Li Qingquan*(病理学系), LingYun, ZhouYaming. Bioisosteric replacements of the indole moiety for the development of a potent and selective PI3K delta inhibitor: Design, synthesis and biological evaluation. European Journal Of Medicinal Chemistry. 2021