毛应启梁

  • 教育经历

  • 工作经历

  • 获得奖项

  • 研究方向

  • 科研项目

  • 讲授课程

  • 学术兼职

  • 代表性论著

  • 1997.9—2002.7 复旦大学上海医学院(原上海医科大学)基础医学专业本科生

  • 2002.9—2007.7 复旦大学上海医学院中西医结合基础专业博士研究生

  • 2007.7—2014.12 复旦大学基础医学院中西医结合学系讲师

  • 2011.11—2012.8 美国 University of Illinois at Urbana-Champaign动物科学系博士后

  • 2012.8—2013.11 美国MD Anderson Cancer Center症状研究系博士后

  • 2014.12 —至今  复旦大学基础医学院中西医结合学系副教授

  • 2016 中国中西医结合学会科技进步奖二等奖(第4完成人)

  • 针刺缓解神经痛、炎症痛、癌痛的神经生物学机制研究

  • 针刺缓解化疗引起感觉异常的作用机制研究

  • 2018,国家自然科学基金面上项目,脊髓GRK2/Eapc1调控小胶质细胞活化在电针缓解顺铂化疗致感觉异常中的作用机制研究,主持

  • 2014,国家自然科学基金面上项目,脊髓GRK2/Epac1调控小胶质细胞表型转化在电针缓解慢性痛中的作用研究,主持

本科生课程:

  • 疼痛生物医学、中西医结合基础概论、中西医学大师与人文素养

研究生课程:

  • 疼痛生物医学、疼痛研究技术与方法、中西医结合基础概论、神经科学原理、医学研究生学习导引

  • 2020-今 上海市医学会疼痛学专科分会基础学组 委员

  • 2019-今 中国神经科学学会感觉与运动分会 委员

  • 2019-今 上海市医学会麻醉专科分会疼痛学组 委员

  • 2019-今 上海市中西医结合学会疼痛与麻醉专业委员会疼痛与康复学组 委员

  1. Chen, Y.#, Zhou, Y.#, Li, X.C., Ma, X., Mi, W.L., Chu, Y.X., Wang, Y.Q.,Mao-Ying, Q.L.* Neuronal GRK2 regulates microglial activation and contributes to electroacupuncture analgesia on inflammatory pain in mice. Biol Res, 55(1):5, 2022

  2. Ma, X., Chen, Y., Li, X.C., Mi, W.L., Chu, Y.X., Wang, Y.Q., Mao-Ying, Q.L.* Spinal Neuronal GRK2 Contributes to Preventive Effect by Electroacupuncture on Cisplatin-Induced Peripheral Neuropathy in Mice. Anesth Analg, 134(1): 204-215, 2022

  3. Hu, L.Y., Mi, W.L., Wu, G.C., Wang, Y.Q., Mao-Ying, Q.L.* Prevention and Treatment for Chemotherapy-Induced Peripheral Neuropathy: Therapies Based on CIPN Mechanisms. Curr Neuropharmacol, 17(2):184-196, 2019

  4. Hu, L.Y. #, Zhou, Y. #, Cui, W.Q., Hu, X.M., Du, L.X., Mi, W.L., Chu, Y.X., Wu, G.C., Wang, Y.Q., Mao-Ying, Q.L.* Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) dependent microglial activation promotes cisplatin-induced peripheral neuropathy in mice. Brain Behav Immun, 68: 132-145, 2018

  5. Liu, H., Liu, S.B., Li, Q., Wang, H., Wang, Y.Q., Mao-Ying, Q.L.* Downregulation of Spinal G Protein-Coupled Kinase 2 Abolished the Antiallodynic Effect of Electroacupuncture. Evid Based Complement Alternat Med, 2015:848603, 2015

  6. Mao-Ying, Q.L., Kavelaars, A., Krukowski, K., Huo, X.J., Zhou, W., Price, T.J., Cleeland, C., Heijnen, C.J. The anti-diabetic drug metformin protects against chemotherapy-induced peripheral neuropathy in a mouse model. PLoS One, 23;9(6):e100701, 2014

  7. Mao-Ying, Q.L., Wang, X.W., Yang, C.J., Li, X., Mi, W.L., Wu, G.C., Wang, Y.Q.* Robust spinal neuroinflammation mediates mechanical allodynia in Walker 256 induced bone cancer rats. Mol Brain, 5:16, 2012

  8. Mao-Ying, Q.L., Zhao, J., Dong, Z.Q., Wang, J., Yu, J., Yan, M.F., Zhang, Y.Q., Wu, G.C., Wang, Y.Q. * A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells. Biochemical and Biophysical Research Communication, 345: 1292-1298, 2006

  9. Mao-Ying, Q.L., Cui, K.M., Liu, Q., Dong, Z.Q., Wang, W., Wang, J., Sha, H., Wu, G.C., Wang, Y.Q. * Stage-dependent analgesia of electro-acupuncture in a mouse model of cutaneous cancer pain. European Journal of Pain, 10(8): 689-94, 2006

  10. Mao-Ying, Q.L., Mi, W.L. Acupuncture Analgesia in Clinical Practice. (Editors: Ying Xia, Xiaoding Cao, Gencheng Wu, Jieshi Cheng, Acupuncture therapy for neurological diseases: A neurobiological view).  TSINGHUA and Springer; 1st Edition 2010, p162-193.(英文专著)